| / English Dictionary |
ACTIN
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
One of the proteins into which actomyosin can be split; can exist in either a globular or a fibrous form
Classified under:
Hypernyms ("actin" is a kind of...):
simple protein (a protein that yields only amino acids when hydrolyzed)
Holonyms ("actin" is a substance of...):
actomyosin (a protein complex in muscle fibers; composed of myosin and actin; shortens when stimulated and causes muscle contractions)
Context examples:
The cytoplasm can be distinguished from the surrounding matrix because of actin filaments, myosin and other muscle proteins arranged to suggest a contractile ability.
(Myofibroblast, NCI Thesaurus)
This protein is involved in both actin binding and cytoskeletal modeling.
(Myosin-XVIIIa, NCI Thesaurus)
This allele, which encodes PDZ and LIM domain protein 4, may play a role in the modulation of the structure of the actin cytoskeleton.
(PDLIM4 wt Allele, NCI Thesaurus)
This gene plays a role in cytoskeletal modeling via regulation of actin fiber turnover.
(PDLIM4 Gene, NCI Thesaurus)
This protein is involved in actin binding, cell migration and cell adhesion.
(PDZ and LIM Domain Protein 2, NCI Thesaurus)
The activated Akt phosphorylates the Edg1 receptor on threonine 236 leading to the activation of Rac1 and subsequent signals leading to actin assembly, chemotaxis and lamellipodia formation.
(Phospholipid Signaling Pathway, NCI Thesaurus/BIOCARTA)
One of the molecular targets of signaling by Eph kinases and ephrins is the actin cytoskeleton, which also plays a role in platelet activation.
(Platelet Aggregation Pathway, NCI Thesaurus/BIOCARTA)
This protein plays a role in cell adhesion, integrin-mediated signal transduction and actin remodeling.
(Paxillin, NCI Thesaurus)
This gene is involved in the organization of the actin cytoskeleton.
(PALLD Gene, NCI Thesaurus)
NCK2-dependent (SH2 domain) B ephrin signaling increases FAK activity, redistributes paxillin, inhibits focal adhesions, and disassembles F-actin fibers.
(NCK Adaptor Protein 2, NCI Thesaurus)
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