| / English Dictionary |
ACTIVATOR
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
(biology) any agency bringing about activation; a molecule that increases the activity of an enzyme or a protein that increases the production of a gene product in DNA transcription
Classified under:
Hypernyms ("activator" is a kind of...):
substance (the real physical matter of which a person or thing consists)
Domain category:
biological science; biology (the science that studies living organisms)
Hyponyms (each of the following is a kind of "activator"):
activating agent ((mineral extraction) a surface-active chemical used in flotation process to increase the attraction to a specific mineral)
accelerator; catalyst ((chemistry) a substance that initiates or accelerates a chemical reaction without itself being affected)
sensitiser; sensitizer ((chemistry) a substance other than a catalyst that facilitates the start of a catalytic reaction)
Antonym:
inhibitor (a substance that retards or stops an activity)
Derivation:
activate (make active or more active)
Context examples:
This gene plays a role both as an activator and repressor of transcription.
(MYBBP1A Gene, NCI Thesaurus)
NF-kB is a heterodimer complex of two DNA-binding subunits from two families of ubiquitous, inducible, nuclear transcription activators involved in cytokine-induced activation of gene expression.
(NF-kB, NCI Thesaurus)
Ubiquitous, inducible, nuclear transcriptional activator that binds to enhancer elements in many different cell types and is activated by pathogenic stimuli.
(NF-kB, NLM, Medical Subject Headings)
This suggests that other co-activators might also have specific repressors, adding another layer of combinatorial complexity in transcriptional regulation.
(PGC1a Regulation Pathway, NCI Thesaurus/BIOCARTA)
This allele, which encodes E3 SUMO-protein ligase PIAS3 protein, plays a role in both signal transducer and activator of transcription family- and steroid hormone-mediated signal transduction.
(PIAS3 wt Allele, NCI Thesaurus)
The determination of the amount of plasminogen activator inhibitor-1 present in a sample.
(Plasminogen Activator Inhibitor-1 Measurement, NCI Thesaurus)
A measurement of the plasminogen activator inhibitor-1 antigen in a biological specimen.
(Plasminogen Activator Inhibitor-1 Antigen Measurement, NCI Thesaurus/CDISC)
A measurement of the plasminogen activator inhibitor-1 in a biological specimen.
(Plasminogen Activator Inhibitor-1 Measurement, NCI Thesaurus/CDISC)
This allele, which encodes tissue-type plasminogen activator protein, is involved in the regulation of plasmin-mediated proteolysis via the conversion of the proenzyme plasminogen to plasmin.
(PLAT wt Allele, NCI Thesaurus)
This allele, which encodes urokinase-type plasminogen activator protein, plays a role in the degradation of the extracellular matrix via activation of plasminogen.
(PLAU wt Allele, NCI Thesaurus)
YOU MAY ALSO LIKE
