| / English Dictionary |
ALKYLATING AGENT
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
An antineoplastic drug used to treat some forms of cancer
Classified under:
Nouns denoting man-made objects
Hypernyms ("alkylating agent" is a kind of...):
antineoplastic; antineoplastic drug; cancer drug (any of several drugs that control or kill neoplastic cells; used in chemotherapy to kill cancer cells; all have unpleasant side effects that may include nausea and vomiting and hair loss and suppression of bone marrow function)
Hyponyms (each of the following is a kind of "alkylating agent"):
chlorambucil; Leukeran (an alkylating agent (trade name Leukeran) used to treat some kinds of cancer)
Context examples:
Alkylating agents with non-specific classification based on mechanism of action, therapeutic use, or chemical properties.
(Miscellaneous Alkylating Agent, NCI Thesaurus)
Brominated analog of MANNITOL which is an antineoplastic agent appearing to act as an alkylating agent.
(Mitobronitol, NLM, Medical Subject Headings)
Any of a class of alkylating agents that contain both a nitroso group and a urea.
(Nitrosourea Compound, NCI Thesaurus)
Inhibition of O6-Alkylguanine-DNA alkyltransferase increases the effectiveness of DNA alkylating agents.
(O6-Alkylguanine-DNA Alkyltransferase Inhibitor, NCI Thesaurus)
A chloroethylnitrosourea compound and an alkylating agent with antineoplastic property.
(PCNU, NCI Thesaurus)
One of a number of chemically-related alkylating agents with antineoplastic properties.
(Phosphoramide Mustard, NCI Thesaurus)
A group of alkylating agents derived from mustard gas, with the sulfur replaced by nitrogen.
(Nitrogen Mustard Compound, NLM, Medical Subject Headings)
It may occur de novo or as a result of exposure to alkylating agents and/or radiotherapy.
(Myelodysplastic syndrome, NCI Thesaurus/WHO)
Any of a class of anti-tumor antibiotics acting as alkylating agents.
(Mitomycin Antineoplastic Antibiotic, NCI Thesaurus)
A prodrug of imidazotetrazine alkylating agent with antineoplastic property.
(Mitozolomide, NCI Thesaurus)
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