| / English Dictionary |
ALS
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
Thickening of tissue in the motor tracts of the lateral columns and anterior horns of the spinal cord; results in progressive muscle atrophy that starts in the limbs
Synonyms:
ALS; amyotrophic lateral sclerosis; Lou Gehrig's disease
Classified under:
Nouns denoting stable states of affairs
Hypernyms ("ALS" is a kind of...):
nervous disorder; neurological disease; neurological disorder (a disorder of the nervous system)
induration; sclerosis (any pathological hardening or thickening of tissue)
Context examples:
No one knows what causes ALS.
(Amyotrophic Lateral Sclerosis, NIH: National Institute of Neurological Disorders and Stroke)
In addition, less IGF-I is circulating in the complex with ALS and IGFBP-3 as a result of increased proteolysis of IGFBP-3.
(Food Intake and Energy Homeostasis Pathway, NCI Thesaurus/BIOCARTA)
ALS is a progressive and terminal disease that damages the function of nerves and muscle.
(Mechanism behind neuron death in motor neurone disease and frontotemporal dementia discovered, University of Cambridge)
However, there’s no evidence that people with glaucoma are at greater risk of developing ALS.
(Glaucoma-related genes revealed, NIH)
A breathing machine can help, but most people with ALS die from respiratory failure.
(Amyotrophic Lateral Sclerosis, NIH: National Institute of Neurological Disorders and Stroke)
A common characteristic of ALS and frontotemporal dementia is the build-up of clumps of misfolded RNA-binding proteins, including a protein called FUS, in the brain and spinal cord.
(Mechanism behind neuron death in motor neurone disease and frontotemporal dementia discovered, University of Cambridge)
Amyotrophic lateral sclerosis (ALS) is a nervous system disease that attacks nerve cells called neurons in your brain and spinal cord.
(Amyotrophic Lateral Sclerosis, NIH: National Institute of Neurological Disorders and Stroke)
Scientists from the University of Cambridge and University of Toronto have identified the molecular mechanism that leads to the death of neurons in amyotrophic lateral sclerosis (also known as ALS or motor neurone disease) and a common form of frontotemporal dementia.
(Mechanism behind neuron death in motor neurone disease and frontotemporal dementia discovered, University of Cambridge)
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