| / English Dictionary |
AMPLIFICATION
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
(electronics) the act of increasing voltage or power or current
Classified under:
Nouns denoting acts or actions
Hypernyms ("amplification" is a kind of...):
increase; step-up (the act of increasing something)
Domain category:
electricity (a physical phenomenon associated with stationary or moving electrons and protons)
Sense 2
Meaning:
Addition of extra material or illustration or clarifying detail
Example:
an elaboration of the sketch followed
Synonyms:
Classified under:
Nouns denoting acts or actions
Hypernyms ("amplification" is a kind of...):
expanding upon; expansion (adding information or detail)
Sense 3
Meaning:
The amount of increase in signal power or voltage or current expressed as the ratio of output to input
Synonyms:
amplification; gain
Classified under:
Nouns denoting attributes of people and objects
Hypernyms ("amplification" is a kind of...):
increase; increment (the amount by which something increases)
Hyponyms (each of the following is a kind of "amplification"):
loop gain ((telecommunication) the gain of a feedback amplifier or system as a function of how much output is fed back to the input)
Context examples:
ERBB proteins are over expressed in a significant portion of adenocarcinomas at various sites, especially in the breast; gene amplification appears to be the predominant cause of over expression.
(Oncogene ERB B, NCI Thesaurus)
NMYC amplification is associated with oncogenic transformation.
(Oncogene MYCN, NCI Thesaurus)
The T cell costimulatory signal provided by the OX40/OX40L interaction increases the clonal amplification of antigen-specific T cells and the survival of memory T cells that respond to this antigen.
(OX40 Signaling Pathway, NCI Thesaurus/BIOCARTA)
Wild-type molecules are rendered inactive for amplification by binding of a peptide nucleic acid (PNA) probe that hybridizes to wild-type sequence with greater affinity and under less stringent conditions.
(Peptide Nucleic Acid Clamping, NCI Thesaurus)
Any of various amplification and detection strategies applied to detection of virus contamination in donor blood.
(Nucleic Acid Amplification Test, NCI Thesaurus)
Following amplification of reverse transcriptase polymerase chain reaction assay, the quantified amount of the target gene divided by the quantified amount of housekeeping gene.
(Normalized Quotient, NCI Thesaurus)
Translocation of phosphorylated ERK/MAPK to the nucleus leads to amplification and de-restriction of TFF expression to ensure sustained action.
(Mucosal Healing Pathway, NCI Thesaurus/BIOCARTA)
This gene is involved in transcriptional regulation and amplification of this gene is associated with a variety of tumors, most notably neuroblastomas.
(MYCN Gene, NCI Thesaurus)
Contrast media that has a lower amplification and intensity than the surrounding tissue making the contrast look less opaque when seen in an x-ray.
(Negative Contrast Agent, NCI Thesaurus)
Amplification of this gene is associated with the development of hormone-resistant prostate cancer.
(FGR wt Allele, NCI Thesaurus)
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