| / English Dictionary |
ANAPLASTIC
| Pronunciation (US): |  | (GB): | |
I. (adjective)
Sense 1
Meaning:
Of or relating to anaplasia
Classified under:
Relational adjectives (pertainyms)
Pertainym:
anaplasia (loss of structural differentiation within a cell or group of cells often with increased capacity for multiplication, as in a malignant tumor)
Derivation:
anaplasia (loss of structural differentiation within a cell or group of cells often with increased capacity for multiplication, as in a malignant tumor)
Context examples:
A monoclonal antibody that binds to cells that have the CD30 antigen on their surface, including Hodgkin disease cells and cells from anaplastic large cell lymphoma, and cutaneous T-cell lymphoma.
(Monoclonal Antibody SGN-30, NCI Dictionary)
A high grade glial neoplasm consisting chiefly of undifferentiated anaplastic cells of glial origin that show marked nuclear pleomorphism.
(Mouse Glioblastoma, NCI Thesaurus/MMHCC)
The malignant mural nodules histologically are anaplastic carcinomas, carcinosarcomas, or sarcomas.
(Ovarian Mucinous Cystic Tumor with Mural Nodules, NCI Thesaurus)
In poorly differentiated cases the malignant epithelial cells show anaplastic features.
(Ovarian Serous Cystadenocarcinoma, NCI Thesaurus)
A carcinoma that arises from the parotid gland and is characterized by the presence of undifferentiated, anaplastic malignant epithelial cells.
(Parotid Gland Undifferentiated Carcinoma, NCI Thesaurus)
For lesions with significant mitotic activity (5 or more mitoses per 10 HPF) and/or with areas of necrosis, the designation "pleomorphic xanthoastrocytoma with anaplastic features" may be used.
(Pleomorphic Xanthoastrocytoma, NCI Thesaurus/WHO)
WHO grading system recognizes two malignancy grades: WHO grade II for well-differentiated tumors (oligodendroglioma) and WHO grade III for anaplastic oligodendroglioma.
(Oligodendroglial tumor, NCI Thesaurus/Adapted from WHO)
T-cell non-Hodgkin lymphomas include mycosis fungoides, anaplastic large cell lymphoma, and precursor T-lymphoblastic lymphoma.
(non-Hodgkin lymphoma, NCI Dictionary)
A chromosomal translocation t(X;2)(q11;p23) of this gene and the ALK gene is associated with anaplastic large cell lymphoma.
(MSN wt Allele, NCI Thesaurus)
A chromosomal translocation t(2;22)(p23;q12) of this gene and the ALK gene is associated with anaplastic large cell lymphoma.
(MYH9 wt Allele, NCI Thesaurus)
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