| / English Dictionary |
ANGIOTENSIN I
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
A physiologically inactive form of angiotensin that is the precursor to angiotensin II
Classified under:
Nouns denoting man-made objects
Hypernyms ("angiotensin I" is a kind of...):
angiotensin; angiotonin; Hypertensin (any of several vasoconstrictor substances (trade name Hypertensin) that cause narrowing of blood vessels)
Context examples:
Enalaprilat competitively binds to and inhibits ACE, thereby blocking the conversion of angiotensin I to angiotensin II.
(Enalapril, NCI Thesaurus)
Idrapril competitively binds to and inhibits ACE, thereby blocking the conversion of angiotensin I to angiotensin II.
(Idrapril, NCI Thesaurus)
By competing with angiotensin I for ACE, deserpidine blocks the conversion of angiotensin I to angiotensin II, which is a potent vasoconstrictor.
(Deserpidine, NCI Thesaurus)
This protein plays a role in the hydrolysis of angiotensin I to form angiotensin II and the solubilization of glycophophoinositol-anchored proteins from the plasma membrane.
(Angiotensin-Converting Enzyme, NCI Thesaurus)
The determination of the amount of angiotensin I hormone present in a sample.
(Angiotensin I Measurement, NCI Thesaurus)
Aliskiren selectively binds to the S3 sub-pocket of renin, an enzyme in the renin-angiotensin-aldosterone system (RAAS) that is responsible for converting angiotensinogen to angiotensin I (AT I).
(Aliskiren, NCI Thesaurus)
As a prodrug, alacepril is rapidly metabolized to captopril; captopril competitively binds to and inhibits ACE, thereby blocking the conversion of angiotensin I to angiotensin II.
(Alacepril, NCI Thesaurus)
Angiotensinogen is digested by renin to produce angiotensin I (AGT I).
(Angiotensin-converting Enzyme 2 Pathway, NCI Thesaurus/BIOCARTA)
A measurement of the angiotensin I hormone in a biological specimen.
(Angiotensin I Measurement, NCI Thesaurus/CDISC)
As a prodrug cilazapril is rapidly metabolized in the liver to cilazaprilat; cilazaprilat competitively binds to and inhibits ACE, thereby blocking the conversion of angiotensin I to angiotensin II.
(Cilazapril Anhydrous, NCI Thesaurus)
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