| / English Dictionary |
BACTERIOPHAGE
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
A virus that is parasitic (reproduces itself) in bacteria
Example:
phage uses the bacterium's machinery and energy to produce more phage until the bacterium is destroyed and phage is released to invade surrounding bacteria
Synonyms:
Classified under:
Hypernyms ("bacteriophage" is a kind of...):
virus ((virology) ultramicroscopic infectious agent that replicates itself only within cells of living hosts; many are pathogenic; a piece of nucleic acid (DNA or RNA) wrapped in a thin coat of protein)
Hyponyms (each of the following is a kind of "bacteriophage"):
coliphage (a bacteriophage that infects the bacterium Escherichia coli)
typhoid bacteriophage (a bacteriophage specific for the bacterium Salmonella typhi)
Derivation:
bacteriophagic; bacteriophagous (of or relating to bacteriophages)
Context examples:
The science concerned with the genes and genetic structure of bacteriophages.
(Bacteriophage Genetics, NCI Thesaurus)
The most frequently used typing systems are bacteriophage typing, serotyping, bacteriocin typing, and biotyping.
(Bacterial Typing Procedure, NCI Thesaurus)
Such a vector includes at least one cos site, the target for DNA uptake into bacteriophage particles and integration into the host genome.
(Cosmid Vector, NCI Thesaurus)
Using a mouse model of alcohol-associated liver disease, mice were transplanted with stool from cytolysin-positive alcoholic hepatitis patients and treated with a cocktail of bacteriophages targeting the cytolytic E. faecalis strains.
(Bacteriophage therapy may ease severity of alcoholic hepatitis, National Institutes of Health)
Administration of E. faecalis-targeting bacteriophage also significantly reduced levels of cytolysin in the liver.
(Bacteriophage therapy may ease severity of alcoholic hepatitis, National Institutes of Health)
Dr. Schnabl and his colleagues then investigated the therapeutic potential of bacteria-killing viruses known as bacteriophages that specifically target cytolytic E. faecalis.
(Bacteriophage therapy may ease severity of alcoholic hepatitis, National Institutes of Health)
Taken together, our findings link cytolytic E. faecalis with worse clinical outcomes and mortality in humans with alcoholic hepatitis, and that bacteriophages can specifically target cytolytic E. faecalis in a mouse model of alcohol-induced liver disease, said Dr. Schnabl.
(Bacteriophage therapy may ease severity of alcoholic hepatitis, National Institutes of Health)
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