| / English Dictionary |
BASE PAIR
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
One of the pairs of chemical bases joined by hydrogen bonds that connect the complementary strands of a DNA molecule or of an RNA molecule that has two strands; the base pairs are adenine with thymine and guanine with cytosine in DNA and adenine with uracil and guanine with cytosine in RNA
Classified under:
Hypernyms ("base pair" is a kind of...):
base; nucleotide (a phosphoric ester of a nucleoside; the basic structural unit of nucleic acids (DNA or RNA))
Holonyms ("base pair" is a part of...):
deoxyribonucleic acid; desoxyribonucleic acid; DNA ((biochemistry) a long linear polymer found in the nucleus of a cell and formed from nucleotides and shaped like a double helix; associated with the transmission of genetic information)
Context examples:
Chromosome 18 spans about 76 million base pairs and represents about 2.5% of the total DNA in normal diploid cells.
(Chromosome 18, NCI Thesaurus)
Chromosome 6 spans more than 170 million base pairs and represents between 5.5 and 6% of the total DNA in normal diploid cells.
(Chromosome 6, NCI Thesaurus)
Chromosome 7 spans more than 158 million base pairs and represents between 5 and 5.5% of the total DNA in normal diploid cells.
(Chromosome 7, NCI Thesaurus)
Nucleosome core particle consists of the 146 base pair highly protected DNA segment and its bound histone octamer (two of each histones H2A, histone2B,, H3 and H4).
(Nucleosome Core Particle, NCI Thesaurus)
The repeating structural units of chromatin, each consisting of approximately 200 base pairs of DNA wound around a protein core.
(Nucleosome, NCI Thesaurus)
As the stabilized active metabolite of ifosfamide, palifosfamide irreversibly alkylates and crosslinks DNA through GC base pairs, resulting in irreparable 7-atom interstrand crosslinks.
(Palifosfamide Tromethamine, NCI Thesaurus)
Doxorubicin intercalates between DNA base pairs, thereby hinders the movement of replication machinery along DNA strands, as well as blocks the activity of topoisomerase II during replication.
(Pegylated Liposomal Doxorubicin Hydrochloride, NCI Thesaurus)
Distance is measured in base pairs.
(Physical Map of the Human Genome, NCI Thesaurus)
Nucleosomal repeat length is approximately 200 base pairs of DNA within which 146 base pairs are highly protected.
(Nucleosomal Repeat Length, NCI Thesaurus)
SMAD3 and SMAD4 proteins specifically recognize an eight base pair palindromic DNA sequence that confers TGF-beta responsiveness to a minimal promoter.
(Mothers Against Decapentaplegic Homolog 3, NCI Thesaurus)
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