| / English Dictionary |
BLOCKED
| Pronunciation (US): |  | (GB): | |
I. (adjective)
Sense 1
Meaning:
Completely obstructed or closed off
Example:
the drain was plugged
Synonyms:
blocked; plugged
Classified under:
Similar:
obstructed (shut off to passage or view or hindered from action)
Sense 2
Meaning:
Closed to traffic
Example:
the repaving results in many blocked streets
Classified under:
Similar:
closed (not open or affording passage or access)
II. (verb)
Sense 1
Past simple / past participle of the verb block
Context examples:
The beneficial effects of the calorie restriction could be blocked, however, by providing the mice with extra methionine and cysteine.
(Pathways Underlying the Benefits of Calorie Restriction, NIH)
In other words, ketamine had blocked the effects of over-activating area 25, which would otherwise blunt anticipation.
(Marmoset study gives insights into loss of pleasure in depression, University of Cambridge)
That oxytocin receptor interneurons released a molecule called CRHBP that blocked the activity of CRH.
(Anxiety molecules affect male and female mice differently, NIH)
The dark patch to the left of center is swaddled in so much dust, even the infrared light is blocked.
(The 'Serpent' star-forming cloud hatches new stars, NASA)
By inhibiting the formation of the complex between androgen activated AR- and the AP1 transcription factor JunD, the expression of androgen-responsive genes are blocked.
(Androgen Antagonist APC-100, NCI Thesaurus)
BMP signaling can also be blocked by the BMP antagonists noggin and chordin, which are secreted from the notochord and cooperate with Wnts to prevent cardiogenesis.
(ALK Pathway, NCI Thesaurus/BIOCARTA)
A painful swelling of the breasts due to accumulation of milk in blocked lactating ducts.
(Breast Engorgement, NCI Thesaurus)
A condition in which the bronchioles (tiny branches of air tubes in the lungs) become inflamed and blocked.
(Bronchiolitis obliterans, NCI Dictionary)
This may be done to drain urine from a blocked kidney or blocked ureter into a bag outside the body.
(Nephrostomy, NCI Dictionary)
Upstream activation of PI 3 kinase activity that leads to oncogenic transformation can be blocked by inhibition of mTOR by rapamycin.
(mTOR Signaling Pathway BioCarta, NCI Thesaurus/BIOCARTA)
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