/ English Dictionary

BLOCKING

Pronunciation (US):

(GB):

 I. (noun) 

Sense 1

Meaning:

The act of obstructing or deflecting someone's movements

Synonyms:

block; blocking

Classified under:

Nouns denoting acts or actions

Hypernyms ("blocking" is a kind of...):

obstruction (getting in someone's way)

Hyponyms (each of the following is a kind of "blocking"):

interference ((American football) blocking a player's path with your body)

trap block ((American football) an illegal block)

parry ((fencing) blocking a lunge or deflecting it with a circular motion of the sword)

Derivation:

block (impede the movement of (an opponent or a ball))

block (block passage through)

block (render unsuitable for passage)

 II. (verb) 

Sense 1

-ing form of the verb block

Credits

 Context examples: 

Blocking mTOR’s action may keep cancer cells from growing and prevent the growth of new blood vessels that tumors need to grow.

(mTOR inhibitor, NCI Dictionary)

Blocking mTOR may cause the cancer cells to die.

(mTOR, NCI Dictionary)

Acolbifene acts as an estrogen antagonist in uterine and breast tissue, thereby blocking the effects of estrogen in these tissues.

(Acolbifene hydrochloride, NCI Thesaurus)

Blocking CAR activation with an antagonist protects against acetaminophen liver toxicity, suggesting a strategy to treat acetaminophen toxicity.

(Acetaminophen Pathway, NCI Thesaurus/BIOCARTA)

Blocking this may cause cancer cells to die.

(AMG 102, NCI Dictionary)

Blocking ACE, Benazepril decreases vasopressive plasma angiotensin II.

(Amlodipine Besylate/Benazepril Hydrochloride, NCI Thesaurus)

By blocking these inhibitory receptors, NK cells become activated and attack cancer cells leading to tumor cell death.

(Anti-KIR Monoclonal Antibody IPH2102, NCI Thesaurus)

Anti-IL-6 chimeric monoclonal antibody works by blocking inflammation and tumor growth.

(anti-IL-6 chimeric monoclonal antibody, NCI Dictionary)

Upon intravenous administration, the anti-MIF MoAb binds to MIF, blocking its activity and preventing the MIF-mediated secretion of certain cytokines, including interleukin-1 beta and tumor necrosis factor-alpha.

(Anti-Macrophage Migration Inhibitory Factor Monoclonal Antibody, NCI Thesaurus)

Upon administration, anti-myostatin monoclonal antibody LY2495655 binds to and neutralizes the MSTN protein, thereby blocking the MSTN signalling pathway.

(Anti-myostatin Monoclonal Antibody LY2495655, NCI Thesaurus)

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