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BREAKDOWN

Pronunciation (US): Play  (GB): Play

 I. (noun) 

Sense 1

Meaning:

The act of disrupting an established order so it fails to continueplay

Example:

his warning came after the breakdown of talks in London

Synonyms:

breakdown; dislocation

Classified under:

Nouns denoting acts or actions

Hypernyms ("breakdown" is a kind of...):

disruption; perturbation (the act of causing disorder)

Derivation:

break down (make ineffective)

Sense 2

Meaning:

An analysis into mutually exclusive categoriesplay

Synonyms:

breakdown; partitioning

Classified under:

Nouns denoting cognitive processes and contents

Hypernyms ("breakdown" is a kind of...):

analysis; analytic thinking (the abstract separation of a whole into its constituent parts in order to study the parts and their relations)

Hyponyms (each of the following is a kind of "breakdown"):

resolution; resolving (analysis into clear-cut components)

Derivation:

break down (make a mathematical, chemical, or grammatical analysis of; break down into components or essential features)

Sense 3

Meaning:

A cessation of normal operationplay

Example:

there was a power breakdown

Synonyms:

breakdown; equipment failure

Classified under:

Nouns denoting natural events

Hypernyms ("breakdown" is a kind of...):

failure (an event that does not accomplish its intended purpose)

Hyponyms (each of the following is a kind of "breakdown"):

brake failure (brakes fail to stop a vehicle)

engine failure (engine does not run)

dud; misfire (an explosion that fails to occur)

outage (a temporary suspension of operation (as of computers))

power failure; power outage (equipment failure resulting when the supply of power fails)

fault ((electronics) equipment failure attributable to some defect in a circuit (loose connection or insulation failure or short circuit etc.))

Derivation:

break down (stop operating or functioning)

Sense 4

Meaning:

(biology) the process of decay caused by bacterial or fungal actionplay

Synonyms:

breakdown; decomposition; putrefaction; rot; rotting

Classified under:

Nouns denoting natural processes

Hypernyms ("breakdown" is a kind of...):

decay (the process of gradually becoming inferior)

Domain category:

biological science; biology (the science that studies living organisms)

Derivation:

break down (separate (substances) into constituent elements or parts)

Sense 5

Meaning:

A mental or physical breakdownplay

Synonyms:

breakdown; crack-up

Classified under:

Nouns denoting stable states of affairs

Hypernyms ("breakdown" is a kind of...):

collapse; prostration (an abrupt failure of function or complete physical exhaustion)

Hyponyms (each of the following is a kind of "breakdown"):

nervous breakdown (a severe or incapacitating emotional disorder)

Derivation:

break down (collapse due to fatigue, an illness, or a sudden attack)

break down (lose control of one's emotions)

Credits

 Context examples: 

A finding of leakage of bile due to breakdown of a biliary anastomosis (surgical connection of two separate anatomic structures).

(Biliary Anastomotic Leakage, NCI Thesaurus/CTCAE)

A dark orange, yellow pigment that is the product of the breakdown of iron in the blood; it is conjugated in the liver and excreted in the bile.

(Bilirubin, NCI Thesaurus)

C. testosteroni is found in soil and water, is used in industry to breakdown industrial by-products, and is rarely found to be pathogenic in humans.

(Comamonas testosteroni, NCI Thesaurus)

The breakdown product of creatine, a constituent of muscle tissue, that is excreted by the kidney and whose serum level is used to evaluate kidney function.

(Creatinine, NCI Thesaurus)

Leakage due to breakdown of a pancreatic anastomosis.

(Pancreatic Anastomotic Leakage, NCI Thesaurus)

Activation of cyclin B-Cdc2 causes breakdown of the germinal vesicle and the initiation of oocyte maturation.

(Oocyte Maturation Pathway, NCI Thesaurus/BIOCARTA)

A finding of leakage due to breakdown of a pancreatic anastomosis (surgical connection of two separate anatomic structures).

(Pancreatic Anastomotic Leakage, NCI Thesaurus/CTCAE)

The PEG moiety inhibits proteolytic breakdown and clearance of IFN-a2b, which prolongs its half-life, extends the duration of its therapeutic effects and allows less frequent dosing.

(PEG-Proline-Interferon Alfa-2b, NCI Thesaurus)

The PEG moiety inhibits proteolytic breakdown and clearance of AM0010, which prolongs its half-life, extends the duration of its therapeutic effects and allows less frequent dosing.

(Pegylated Recombinant Human Interleukin-10 AM0010, NCI Thesaurus)

The lysis (breakdown) of cancer cells.

(Oncolysis, NCI Dictionary)




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