| / English Dictionary |
CANCER CELL
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
A cell that is part of a malignant tumor
Classified under:
Hypernyms ("cancer cell" is a kind of...):
neoplastic cell (a cell that is part of tumor)
Holonyms ("cancer cell" is a part of...):
malignance; malignancy ((medicine) a malignant state; progressive and resistant to treatment and tending to cause death)
Context examples:
Some evidence suggests that acetylcysteine may exert an anti-apoptotic effect due to its antioxidant activity, possibly preventing cancer cell development or growth.
(Acetylcysteine, NCI Thesaurus)
Monoclonal antibodies are made in the laboratory and can locate and bind to substances in the body, including cancer cells.
(ABX-EGF, NCI Dictionary)
A protein found on the surface of certain types of normal cells and cancer cells.
(Mesothelin, NCI Dictionary)
The spread or migration of cancer cells from one part of the body (the organ in which it first appeared) to another.
(Metastasis, NCI Thesaurus)
This new research shows, however, that oxygen also suppresses the anticancer activity of T cells, thereby permitting cancer cells that have spread to the lungs to escape immune attack and establish metastatic colonies.
(Oxygen can impair cancer immunotherapy in mice, NIH)
MUC-1 is a hypoglycosylated TAA overexpressed by epithelial cancer cells.
(Ad-sig-hMUC-1/ecdCD40L Vaccine, NCI Thesaurus)
Administration of this vaccine leads to an induction of apoptosis through the expression of RTVP-1 and results in a reduction in cellular proliferation in prostate cancer cells.
(AdRTVP-1-Transduced Prostate Cancer Cell-Based Vaccine, NCI Thesaurus)
Subsequently, the positively charged CLIP 71 moiety of this agent interacts with the negatively charged membrane on the cancer cell surface, which may result in cell membrane disruption and cell lysis.
(Membrane-Disrupting Peptide EP-100, NCI Thesaurus)
This may stimulate the secretion of cytokines and result in cell lysis of mesothelin-expressing cancer cells.
(Mesothelin-specific Chimeric Antigen Receptor-engineered Peripheral Blood Lymphocytes, NCI Thesaurus)
The melanoma peptides contained in the vaccine are upregulated in melanoma cancer cells.
(MELITAC 12.1 Peptide Vaccine, NCI Thesaurus)
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