| / English Dictionary |
CARBOXYL
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
The univalent radical -COOH; present in and characteristic of organic acids
Synonyms:
carboxyl; carboxyl group
Classified under:
Hypernyms ("carboxyl" is a kind of...):
chemical group; group; radical ((chemistry) two or more atoms bound together as a single unit and forming part of a molecule)
Derivation:
carboxyl; carboxylic (relating to or containing the carboxyl group or carboxyl radical)
II. (adjective)
Sense 1
Meaning:
Relating to or containing the carboxyl group or carboxyl radical
Synonyms:
carboxyl; carboxylic
Classified under:
Relational adjectives (pertainyms)
Domain category:
chemical science; chemistry (the science of matter; the branch of the natural sciences dealing with the composition of substances and their properties and reactions)
Pertainym:
carboxyl group (the univalent radical -COOH; present in and characteristic of organic acids)
Derivation:
carboxyl (the univalent radical -COOH; present in and characteristic of organic acids)
Context examples:
Each has a central carbon with an amino group (-NH2), a carboxyl (-COOH) group and a side chain attached.
(Dietary Amino Acid, NCI Thesaurus/CRCH)
Amino Acid Biosynthesis consists of cellular enzymatic reactions that produce amino acids, organic compounds containing an amino and a carboxyl group and often used in protein synthesis by the formation of peptide bonds during ribosomal translation of mRNA.
(Amino Acid Biosynthesis, NCI Thesaurus)
It is comprised of the carboxyl terminal half of both light chains and at least three quarters of each heavy chain starting from the carboxyl terminus and excludes the variable regions of the heavy and light chains.
(Immunoglobulin Constant Region, NCI Thesaurus)
The tumor-associated antigen (TAA) HER2/neu is often overexpressed by a variety of tumor cell types; dHER2 includes amino acids 1-645 or 1-653 of the extracellular domain (ECD) and an immunogenic carboxyl terminal autophosphorylation portion of the intracellular domain (ICD).
(dHER2 Vaccine+AS15 Adjuvant, NCI Thesaurus)
A likely membrane attachment device, farnesylation involves enzymatic covalent addition of farnesyl group(s) (three isoprene units) to polypeptide chains that contain the carboxyl terminal motif CAAX.
(Farnesylation Process, NCI Thesaurus)
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