/ English Dictionary

CASCADE

Pronunciation (US):

(GB):

 I. (noun) 

Sense 1

Meaning:

A sudden downpour (as of tears or sparks etc) likened to a rain shower

Example:

a sudden cascade of sparks

Synonyms:

cascade; shower

Classified under:

Nouns denoting natural events

Hypernyms ("cascade" is a kind of...):

descent (a movement downward)

Sense 2

Meaning:

A succession of stages or operations or processes or units

Example:

separation of isotopes by a cascade of processes

Classified under:

Nouns denoting groupings of people or objects

Hypernyms ("cascade" is a kind of...):

succession (a group of people or things arranged or following in order)

Sense 3

Meaning:

A small waterfall or series of small waterfalls

Classified under:

Nouns denoting natural objects (not man-made)

Hypernyms ("cascade" is a kind of...):

falls; waterfall (a steep descent of the water of a river)

Derivation:

cascade (rush down in big quantities, like a cascade)

 II. (verb) 

Sense 1

Meaning:

Arrange (open windows) on a computer desktop so that they overlap each other, with the title bars visible

Classified under:

Verbs of touching, hitting, tying, digging

Hypernyms (to "cascade" is one way to...):

arrange; set up (put into a proper or systematic order)

Domain category:

computer science; computing (the branch of engineering science that studies (with the aid of computers) computable processes and structures)

Sentence frame:

Somebody ----s something

Sense 2

Meaning:

Rush down in big quantities, like a cascade

Synonyms:

cascade; cascade down

Classified under:

Verbs of walking, flying, swimming

Hypernyms (to "cascade" is one way to...):

come down; descend; fall; go down (move downward and lower, but not necessarily all the way)

Sentence frame:

Something ----s

Derivation:

cascade (a small waterfall or series of small waterfalls)

Credits

 Context examples: 

This gene plays a regulatory role in the complement pathway, which is comprised of a complex proteolytic cascade.

(C3 Gene, NCI Thesaurus)

Reversible binding of calcium with proteins often supports protein structure or induces an alteration of protein activity in enzymatic or cell signaling cascades.

(Calcium Binding Protein, NCI Thesaurus)

The CaMKII autophosphorylation involves a kinase cascade of sorts, with each subunit of the multimeric enzyme acting as both kinase and kinase kinase.

(Calmodulin Pathway, NCI Thesaurus/BIOCARTA)

Neurotrophin/Trk signaling is regulated by connecting a variety of intracellular signaling cascades, which include MAPK pathway, PI-3 kinase pathway, and PLC pathway, transmitting positive signals like enhanced survival and growth.

(Neurotrophin Signaling Pathway, NCI Thesaurus/KEGG)

Edg1 stimulation also leads to the activation of the ERK signaling cascade resulting in anti-apoptotic reversal, proliferation and cell survival.

(Phospholipid Signaling Pathway, NCI Thesaurus/BIOCARTA)

The members of the PLC family play a key role in the signal transduction cascade for many receptors.

(Phospholipid Associated Cell Signaling Pathway, NCI Thesaurus/BIOCARTA)

The vertebrate cascade starts with the absorption of photons by the photoreceptive pigments, the rhodopsins, which consist of a membrane embedded chromophore, 11-cis-retinal, and a G-protein-coupled receptor, opsin.

(Phototransduction Pathway, NCI Thesaurus/KEGG)

Pimecrolimus binds to the receptor macrophilin-12 (FKBP-12) forming a complex that blocks the calcium-dependent signal transduction cascade mediated by calcineurin.

(Pimecrolimus, NCI Thesaurus)

Hydrolytic activity initiates signaling cascades in the cell.

(Phospholipase, NCI Thesaurus)

It modulates the phototransduction cascade by interacting with the beta and gamma subunits of the retinal G-protein transducin.

(Phosducin, NCI Thesaurus/LocusLink)

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