| / English Dictionary |
CDNA
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
Single-stranded DNA that is complementary to messenger RNA or DNA that has been synthesized from messenger RNA by reverse transcriptase
Synonyms:
cDNA; complementary DNA
Classified under:
Hypernyms ("cDNA" is a kind of...):
deoxyribonucleic acid; desoxyribonucleic acid; DNA ((biochemistry) a long linear polymer found in the nucleus of a cell and formed from nucleotides and shaped like a double helix; associated with the transmission of genetic information)
Hyponyms (each of the following is a kind of "cDNA"):
provirus (cDNA copy of the RNA genome of a retrovirus; the genetic material of a virus as incorporated into and able to replicate with the genome of a host cell)
dscDNA (double-stranded cDNA)
Context examples:
Analysis using microarray technology (e.g., cDNA arrays to see gene expression or protein microarrays to profile the pattern of proteins).
(Gene Expression Profiling, NCI Thesaurus)
Methods for building collections of cloned DNA consisting of DNA copies of all the mRNAs produced by a cell type. cDNAs are generated using reverse transcriptase and either an oligo-dT or random primer.
(cDNA Library Construction, NCI Thesaurus)
In the case of a cDNA library the DNA inserts are copies of RNAs that have been reverse-transcribed into DNA prior to cloning.
(cDNA Library, NCI Thesaurus)
A replication-defective adenoviral vector encoding human interferon-gamma (IFN-g) cDNA with potential antineoplastic and immunoregulatory activities.
(Adenovirus-Interferon-Gamma TG1042, NCI Thesaurus)
Specifically, they produced complementary DNA sequences (cDNA) for each protein, which are stretches of DNA with all the pieces not necessary for producing the protein removed.
(New studies may bring slug-made glues closer to use in medicine, Wikinews)
The probes are pools of cDNAs, which are generated after isolating mRNA from cells or tissues in two states that one wishes to compare.
(cDNA Microarray Analysis, NCI Thesaurus)
Any state accompanied by evidence of HIV in the body (positive test for HIV genome, cDNA, proteins, antigens, or antibodies); may be medically asymptomatic or symptomatic; prefer AIDS when appropriate.
(HIV Infection, NIH CRISP Thesaurus)
Transgenic hens carrying recombinant human G-CSF cDNA express the naturally glycosylated recombinant human protein in egg albumen from which glycosylated recombinant human G-CSF AVI-014 is isolated.
(Glycosylated Recombinant Human G-CSF AVI-014, NCI Thesaurus)
Autologous CD34+ hematopoietic stem cells transduced with Lenti-D lentiviral vector encoding the human ATP-binding cassette, sub-family D, member 1 (ABCD1) cDNA, for the potential treatment of childhood cerebral adrenoleukodystrophy (CCALD).
(Lenti-D/ABCD1-transduced Autologous Hematopoietic Stem Cells, NCI Thesaurus)
Any well-defined collection of genetic material used to identify unknown nucleic acids; classically, a collection of expressed cDNA clones representing the genome of a particular organism, used to identify newly purified genes or mRNAs by hybridization.
(Gene Bank, NIH CRISP Thesaurus)
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