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CERTAIN

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 I. (adjective) 

Sense 1

Meaning:

Exercising or taking care great enough to bring assuranceplay

Example:

be sure to lock the doors

Synonyms:

certain; sure

Classified under:

Adjectives

Similar:

careful (exercising caution or showing care or attention)

Sense 2

Meaning:

Established beyond doubt or question; definitely knownplay

Example:

the date for the invasion is certain

Classified under:

Adjectives

Similar:

definite (known for certain)

indisputable; sure (impossible to doubt or dispute)

sure as shooting (absolutely certain)

Attribute:

certainty; foregone conclusion; sure thing (something that is certain)

Antonym:

uncertain (not established beyond doubt; still undecided or unknown)

Sense 3

Meaning:

Having or feeling no doubt or uncertainty; confident and assuredplay

Example:

sure of her friends

Synonyms:

certain; sure

Classified under:

Adjectives

Similar:

confident; convinced; positive (persuaded of; very sure)

Attribute:

certainty (the state of being certain)

assurance; authority; confidence; self-assurance; self-confidence; sureness (freedom from doubt; belief in yourself and your abilities)

Antonym:

uncertain (lacking or indicating lack of confidence or assurance)

Sense 4

Meaning:

Certain to occur; destined or inevitableplay

Example:

he is sure to win

Synonyms:

certain; sure

Classified under:

Adjectives

Similar:

bound; destined ((usually followed by 'to') governed by fate)

doomed; fated ((usually followed by 'to') determined by tragic fate)

foreordained; predestinate; predestined (established or prearranged unalterably)

in for (certain to get or have)

Also:

predictable (capable of being foretold)

Antonym:

uncertain (not certain to occur; not inevitable)

Sense 5

Meaning:

Definite but not specified or identifiedplay

Example:

a certain Mrs. Jones

Classified under:

Adjectives

Similar:

definite (precise; explicit and clearly defined)

Sense 6

Meaning:

Reliable in operation or effectplay

Example:

wood dust is a sure sign of termites

Synonyms:

certain; sure

Classified under:

Adjectives

Similar:

dependable; reliable (worthy of reliance or trust)

Sense 7

Meaning:

Established irrevocablyplay

Example:

his fate is sealed

Synonyms:

certain; sealed

Classified under:

Adjectives

Credits

 Context examples: 

But there is a certain sense of equity that resides in life, and it was this sense in him that resented the unfairness of his being permitted no defence against the stone-throwers.

(White Fang, by Jack London)

You bring with you certain fine conceptions of humanity, manhood, conduct, and such things; but here you will find them misconceptions. I have found it so, I added, with an involuntary sigh.

(The Sea-Wolf, by Jack London)

To be fond of dancing was a certain step towards falling in love; and very lively hopes of Mr. Bingley's heart were entertained.

(Pride and Prejudice, by Jane Austen)

People with certain changes in the gene for melanotropin receptor have a higher risk of developing melanoma (skin cancer that begins in melanocytes).

(Melanotropin receptor, NCI Dictionary)

Memantine hydrochloride blocks the uptake of calcium by certain brain cells and decreases their activity.

(Memantine hydrochloride, NCI Dictionary)

People with certain changes in the gene for melanocortin 1 receptor have a higher risk of developing melanoma (skin cancer that begins in melanocytes).

(Melanocortin 1 receptor, NCI Dictionary)

Mekinist blocks certain proteins, which may help keep cancer cells from growing and may kill them.

(Mekinist, NCI Dictionary)

If the label says don't give to children under a certain age or weight, don't do it.

(Medicines and Children, Food and Drug Administration)

Menatetrenone may act by modulating the signalling of certain tyrosine kinases, thereby affecting several transcription factors including c-myc and c-fos.

(Menatetrenone, NCI Thesaurus)

It may also be used to treat certain other conditions, such as Crohn disease and ulcerative colitis.

(Mercaptopurine, NCI Dictionary)




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