| / English Dictionary |
CHELATE
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
A heterocyclic compound having a metal ion attached by coordinate bonds to at least two nonmetal ions
Synonyms:
chelate; chelate compound
Classified under:
Hypernyms ("chelate" is a kind of...):
heterocycle; heterocyclic; heterocyclic compound (a compound containing a heterocyclic ring)
Derivation:
chelate (form a chelate, in chemistry)
II. (adjective)
Sense 1
Meaning:
Having or resembling chelae or claws
Classified under:
Relational adjectives (pertainyms)
Pertainym:
chela (a grasping structure on the limb of a crustacean or other arthropods)
Sense 2
Meaning:
Relating to or characterized by chelation
Synonyms:
chelate; chelated
Classified under:
Relational adjectives (pertainyms)
Pertainym:
chelation (the process of forming a ring by forming one or more hydrogen bonds)
III. (verb)
Verb forms
Present simple: I / you / we / they chelate ... he / she / it chelates
Past simple: chelated
Past participle: chelated
-ing form: chelating
Sense 1
Meaning:
Form a chelate, in chemistry
Classified under:
Verbs of being, having, spatial relations
Hypernyms (to "chelate" is one way to...):
constitute; form; make (to compose or represent)
Sentence frame:
Something ----s
Derivation:
chelate (a heterocyclic compound having a metal ion attached by coordinate bonds to at least two nonmetal ions)
chelation (the process of forming a ring by forming one or more hydrogen bonds)
chelation ((medicine) the process of removing a heavy metal from the bloodstream by means of a chelate as in treating lead or mercury poisoning)
Context examples:
A derivative of pyridoxyl ethyldiamine (PLED) and mimetic of the human mitochondrial manganese superoxide dismutase (MnSOD), with antioxidant, metal chelating and potential chemoprotective activities.
(PLED-based MnSOD Mimetic, NCI Thesaurus)
Possessing antineoplastic properties, penicillamine induces apoptosis by a p53-mediated mechanism and inhibits angiogenesis by chelating with copper, a cofactor for angiogenesis.
(Penicillamine, NCI Thesaurus)
A monoclonal antibody directed against the neurohormone bombesin that is conjugated to isothiocyanobenzyl diethylenetriaminepentaacetic acid (ITC-D), a bifunctional chelating agent that allows the antibody to be labeled with a metal species.
(MoAb Bombesin (ITC-D), NCI Thesaurus)
Nitrilotriacetic acid is mainly used as a chelating and eluting agent and is found in laundry detergents.
(Nitrilotriacetic Acid, NCI Thesaurus)
An iron-chelating agent that removes iron from tumors by inhibiting DNA synthesis and causing cancer cell death.
(Deferoxamine, NCI Dictionary)
Ammonium tetrathiomolybdate is a type of chelating agent and a type of antiangiogenesis agent.
(Ammonium tetrathiomolybdate, NCI Dictionary)
ATN-224 selectively chelates the copper ion in superoxide dismutase 1 (SOD1) in endothelial cells, thereby depleting SOD1 of copper and inhibiting its activity.
(Bis(choline)tetrathiomolybdate, NCI Thesaurus)
A combination agent composed of the benzo-poly-carbonic-acid polymer BP-Cx1 chelated to platinum with potential antineoplastic activity.
(BP-Cx1-Platinum Complex BP-C1, NCI Thesaurus)
In medicine, chelating agents are used to remove toxic metals from the body.
(Chelating agent, NCI Dictionary)
Inhibited by chelating agents; requires divalent cations for activity.
(Aryldialkylphosphatase, NCI Thesaurus)
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