| / English Dictionary |
CHEMOTHERAPEUTIC
| Pronunciation (US): |  | (GB): | |
I. (adjective)
Sense 1
Meaning:
Of or relating to chemotherapy
Synonyms:
chemotherapeutic; chemotherapeutical
Classified under:
Relational adjectives (pertainyms)
Pertainym:
chemotherapy (the use of chemical agents to treat or control disease (or mental illness))
Derivation:
chemotherapy (the use of chemical agents to treat or control disease (or mental illness))
Context examples:
Defects in MMR are associated with genome-wide instability, predisposition to certain types of cancer including HNPCC, resistance to certain chemotherapeutic agents, and abnormalities in meiosis and sterility in mammalian systems.
(Mismatch Repair Pathway, NCI Thesaurus/KEGG)
Dofequidar has demonstrated reversal of the MDR phenotype in those cells exposed to various chemotherapeutic agents, such as vinca alkaloids and anthracyclines.
(Dofequidar Fumarate, NCI Thesaurus)
Individuals with this disorder may develop a severe toxicity reaction if they are exposed to the chemotherapeutic agent 5-fluorouracil.
(Dihydropyrimidine Dehydrogenase Deficiency, NCI Thesaurus)
A drug that prevents blood cell clumping and enhances the effectiveness of fluorouracil and other chemotherapeutic agents.
(Dipyridamole, NCI Dictionary)
Multidrug Resistance Induction involves initiation of activities of biologic molecules or complexes involved in processes that increase the ability of cancer cells to counteract, defeat, or withstand the effects of multiple chemotherapeutic agents.
(Multidrug Resistance Induction, NCI Thesaurus)
Inhibition results in increased transport of drug into, or decreased transport out of, cells and increased effectiveness of chemotherapeutic agents.
(Multidrug resistance inhibition, NCI Thesaurus)
This agent is shown to act synergistically with chemotherapeutic drugs in multiple cancer models.
(Anti-human GITR Monoclonal Antibody TRX518, NCI Thesaurus)
Hyperhidrosis appears to play a role in the development of certain mucocutaneous reactions, such as palmar-plantar erythrodysesthesia (PPE), upon administration of chemotherapeutic agents such as doxorubicin, 5-fluorouracil, and capecitabine.
(Antiperspirant Cream F511, NCI Thesaurus)
Chemotherapeutic drugs, such as etoposide, are not the only pharmaceuticals that induce DPCs.
(DNA damage caused by cancer treatment reversed by ZATT protein, National Institutes of Health)
In addition, HE3235 may potentiate chemotherapeutic agents by down-regulating ABCG2, the gene encoding the multi-drug resistant (MDR) protein MDR2.
(Androstane Steroid HE3235, NCI Thesaurus)
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