| / English Dictionary |
CLONAL
| Pronunciation (US): |  | (GB): | |
I. (adjective)
Sense 1
Meaning:
Of or relating to a clone
Classified under:
Relational adjectives (pertainyms)
Pertainym:
clone (a group of genetically identical cells or organisms derived from a single cell or individual by some kind of asexual reproduction)
Context examples:
A clonal (malignant) proliferation of myeloid cells originating from a primitive stem cell.
(Myeloid Neoplasm, NCI Thesaurus)
A clonal hematopoietic stem cell disorder, characterized by proliferation in the bone marrow of one or more of the myeloid (i.e., granulocytic, erythroid, megakaryocytic, and mast cell) lineages.
(Myeloproliferative Neoplasm, NCI Thesaurus)
Clonal proliferations arising from cutaneous hair follicles composed in part of cells with basaloid cytology that resemble human pilomatrixomas.
(Pilomatrixoma Type of Basaloid Follicular Neoplasm of the Mouse Skin, NCI Thesaurus/MMHCC)
The T cell costimulatory signal provided by the OX40/OX40L interaction increases the clonal amplification of antigen-specific T cells and the survival of memory T cells that respond to this antigen.
(OX40 Signaling Pathway, NCI Thesaurus/BIOCARTA)
A clonal proliferation of immunoglobulin-secreting plasma cells.
(Plasma Cell Neoplasm, NCI Thesaurus)
Clonal proliferations that arise in the skin that exhibit plasmacytic differentiation.
(Plasma Cell Neoplasms of the Mouse Skin, NCI Thesaurus/MMHCC)
A malignant (clonal) proliferation of plasma cells that are cytologically and immunophenotypically identical to those of plasma cell myeloma, but manifest a localized osseous or extraosseous growth pattern.
(Plasmacytoma, NCI Thesaurus/WHO)
Clonal proliferations arising from cutaneous hair follicles composed in part of cells with basaloid cytology that exhibit features of hair follicle differentiation but are not easily classified as one of the above variants.
(Other Variants of Basaloid Follicular Neoplasm of the Mouse Skin, NCI Thesaurus/MMHCC)
There is clonal rearrangement of the immunoglobulin or the T-cell receptor genes.
(Neoplastic Post-Transplant Lymphoproliferative Disorder, NCI Thesaurus)
An alteration in the normal structure of the skin relative to normal for a specific age, mouse strain, and skin site that does not involve a clonal proliferation of cells.
(Non-neoplastic Disorders of the Mouse Skin, NCI Thesaurus/MMHCC)
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