CLOTTING FACTOR

Pronunciation (US): (GB):

I. (noun)

Sense 1

Meaning:

Any of the factors in the blood whose actions are essential for blood coagulation

Synonyms:

clotting factor; coagulation factor

Classified under:

Nouns denoting substances

Hypernyms ("clotting factor" is a kind of...):

plasma protein (any of the proteins in blood plasma)

Hyponyms (each of the following is a kind of "clotting factor"):

factor I; fibrinogen (a protein present in blood plasma; converts to fibrin when blood clots)

factor II; prothrombin (a protein in blood plasma that is the inactive precursor of thrombin)

factor III; thrombokinase; thromboplastin (an enzyme liberated from blood platelets that converts prothrombin into thrombin as blood starts to clot)

calcium ion; factor IV (ion of calcium; a factor in the clotting of blood)

accelerator factor; factor V; proaccelerin; prothrombin accelerator (a coagulation factor)

cothromboplastin; factor VII; proconvertin; stable factor (a coagulation factor formed in the kidney under the influence of vitamin K)

antihaemophilic factor; antihaemophilic globulin; antihemophilic factor; antihemophilic globulin; factor VIII; Hemofil (a coagulation factor (trade name Hemofil) whose absence is associated with hemophilia A)

Christmas factor; factor IX (coagulation factor whose absence is associated with hemophilia B)

factor X; prothrombinase (coagulation factor that is converted to an enzyme that converts prothrombin to thrombin in a reaction that depends on calcium ions and other coagulation factors)

factor XI; plasma thromboplastin antecedent (coagulation factor whose deficiency results in a hemorrhagic tendency)

factor XII; Hageman factor (coagulation factor whose deficiency results in prolongation of clotting time of venous blood)

factor XIII; fibrinase (in the clotting of blood thrombin catalyzes factor XIII into its active form (fibrinase) which causes fibrin to form a stable clot)

Credits

Context examples:

This prevents gamma carboxylation of glutamic acid residues near the N-terminals of the vitamin K-dependent clotting factors, including factor II, VII, IX, and X and anticoagulant proteins C and S. This prevents their activity and thus thrombin formation.

(Acenocoumarol, NCI Thesaurus)

Clotting factor is a protein needed for normal blood clotting.

(Hemophilia, NIH: National Heart, Lung, and Blood Institute)

For blood to clot, your body needs cells called platelets and proteins known as clotting factors.

(Bleeding Disorders, NIH)