| / English Dictionary |
CMV
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
Any of a group of herpes viruses that enlarge epithelial cells and can cause birth defects; can affect humans with impaired immunological systems
Synonyms:
Classified under:
Hypernyms ("CMV" is a kind of...):
herpes; herpes virus (any of the animal viruses that cause painful blisters on the skin)
Context examples:
A peptide vaccine derived from cytomegalovirus (CMV) antigens with potential immunostimulating activity.
(PEP-CMV Vaccine, NCI Thesaurus)
This results in cell lysis and prevents viral replication and the development of CMV disease.
(Multi-peptide CMV-Modified Vaccinia Ankara Vaccine, NCI Thesaurus)
An anhydrous form of cidofovir, a synthetic, acyclic monophosphate nucleotide analog of deoxycytidine with antiviral activity, mostly used against cytomegalovirus (CMV).
(Cidofovir Anhydrous, NCI Thesaurus)
Patients with AIDS are especially susceptible to opportunistic infections (usually pneumocystis carinii pneumonia, cytomegalovirus (CMV) infections, tuberculosis, candida infections, and cryptococcosis), and the development of malignant neoplasms (usually non-Hodgkin's lymphoma and Kaposi's sarcoma).
(Acquired immunodeficiency syndrome, NCI Thesaurus)
A population of allogeneic cytotoxic T lymphocytes (CTLs) specifically reactive to the herpes virus cytomegalovirus (CMV) with potential immunomodulating and antiviral activities.
(Allogeneic Cytomegalovirus-Specific Cytotoxic T lymphocytes, NCI Thesaurus)
A poloxamer-formulated, bivalent DNA vaccine containing two plasmids encoding both the human cytomegaloviral (CMV) tegument phosphoprotein 65 (pp65), a major internal matrix protein, and glycoprotein B (gB), an important CMV component responsible for attachment and entry into cells, with potential immunostimulatory properties.
(CMVpp65/gB Plasmid Vaccine ASP0113, NCI Thesaurus)
A human serotype 5, replication-defective, first generation adenoviral vector, with the viral E1a and E3 protein encoding regions deleted, which is engineered to express the herpes simplex virus thymidine kinase (HSV-tk) gene under the transcriptional control of the CMV promoter.
(Ad-hCMV-TK, NCI Thesaurus)
A human serotype 5, replication-defective, first generation adenoviral vector, with the viral E1a and E3 protein encoding regions deleted, which is engineered to express the soluble, immune-mediated stimulatory gene human fms-like tyrosine kinase 3 ligand (Flt3L), under the transcriptional control of the CMV promoter, with potential immunostimulating activity.
(Ad-hCMV-Flt3L, NCI Thesaurus)
Containing an expression cassette consisting of the human cytomegalovirus (CMV) promoter and the simian virus 40 (SV40) polyadenylation signal, Ad5CMV is used as a transfer vector for inserting genes of interest into target cells for expression.
(Ad5CMV, NCI Thesaurus)
A preparation of allogeneic Epstein-Barr virus (EBV)- and human cytomegalovirus (CMV)-specific CD8+ central memory-derived T effector-lymphocytes that have been genetically modified to express a chimeric antigen receptor (CAR) anti-CD19/CD3 zeta chain fusion protein coupled to the intracellular signal domain of CD28 antigen, with potential immunostimulating, anti-viral and antineoplastic activities.
(Allogeneic CD19-specific CAR-modified CD8 Plus Central Memory-derived Virus-specific T Cells, NCI Thesaurus)
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