| / English Dictionary |
CODON
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
A specific sequence of three adjacent nucleotides on a strand of DNA or RNA that specifies the genetic code information for synthesizing a particular amino acid
Classified under:
Hypernyms ("codon" is a kind of...):
sequence (serial arrangement in which things follow in logical order or a recurrent pattern)
Context examples:
Internal ribosome entry site (IRES) is a translational cis-acting element that directs ribosomes to the start codon by a cap-independent mechanism.
(Internal Ribosome Entry Site, NCI Thesaurus)
C-myb antisense oligonucleotide G4460 binds to codon sequences 2 to 9 of c-myb mRNA, inhibiting translation of the transcript.
(C-myb Antisense Oligonucleotide G4460, NCI Thesaurus)
The CYP2C19*4 allele exhibits a clinically-relevant SNP (c.1A>G) in the initiation codon that prevents translation of a protein product.
(CYP2C19*4 Allele, NCI Thesaurus)
By using alternative initiation codons in the same reading frame, two isoforms (alpha and beta) are encoded by a single transcript from this gene.
(Caveolin 2, NCI Thesaurus)
In DNA or RNA, a sequence of 3 consecutive nucleotides that codes for a specific amino acid or signals the termination of gene translation (stop or termination codon).
(Codon, NCI Dictionary)
The CYP2D6*11 allele exhibits a clinically-relevant SNP (g.883G>C) that eliminates the splice acceptor site of intron 1 and results in a premature stop codon.
(CYP2D6*11 Allele, NCI Thesaurus)
The CYP2D6*21 allele exhibits a single nucleotide insertion (g.2573insC) in exon 5 that results in a frameshift and generates a stop codon 17 bp downstream of the insertion site.
(CYP2D6*21 Allele, NCI Thesaurus)
The CYP2D6*8 allele exhibits a clinically-relevant SNP (g.1758G>T) in exon 3 that generates a stop codon.
(CYP2D6*8 Allele, NCI Thesaurus)
Five-prime recombinations of MCF2 delete N-terminal codons, producing activated oncogenic variant; the upstream replacing sequence, URS, is derived from D15S93 at 15q15-q23.
(DBL Oncoprotein, NCI Thesaurus)
The CYP2D6*6 allele exhibits a single nucleotide deletion (g.1707delT) in exon 3 that results in a frameshift and generates a stop codon located one codon after the deletion.
(CYP2D6*6 Allele, NCI Thesaurus)
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