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COENZYME A

 I. (noun) 

Sense 1

Meaning:

A coenzyme present in all living cells; essential to metabolism of carbohydrates and fats and some amino acidsplay

Classified under:

Nouns denoting substances

Hypernyms ("coenzyme A" is a kind of...):

coenzyme (a small molecule (not a protein but sometimes a vitamin) essential for the activity of some enzymes)

Credits

 Context examples: 

Water-soluble vitamin that is a component of coenzyme A and phosphopantetheine, which are involved in fatty acid metabolism.

(Pantothenic acid, NCI Thesaurus/CRCH)

A genetic disorder characterized by deficiency of the enzyme long-chain acyl-coenzyme A dehydrogenase that metabolizes long-chain fatty acids.

(Acyl-CoA Dehydrogenase, Long-Chain Deficiency, NCI Thesaurus)

An autosomal recessive inherited disorder characterized by a deficiency of the enzyme very long-chain acyl-coenzyme A dehydrogenase that metabolizes long-chain fatty acids.

(Acyl-CoA Dehydrogenase, Very Long-Chain Deficiency, NCI Thesaurus)

A genetic disorder characterized by deficiency of the enzyme short-chain acyl-coenzyme A dehydrogenase that metabolizes short-chain fatty acids.

(Acyl-CoA Dehydrogenase, Short-Chain Deficiency, NCI Thesaurus)

A genetic disorder characterized by deficiency of the enzyme medium-chain acyl-coenzyme A dehydrogenase that metabolizes medium-chain fatty acids.

(Acyl-CoA Dehydrogenase, Medium-Chain Deficiency, NCI Thesaurus)

This protein binds free fatty acids and their coenzyme a derivatives, bilirubin, and some other small molecules in the cytoplasm.

(Fatty Acid-Binding Protein 1, NCI Thesaurus)

Dexpanthenol acts as a precursor of coenzyme A necessary for acetylation reactions and is involved in the synthesis of acetylcholine.

(Dexpanthenol, NCI Thesaurus)

The 1S isomer of crilvastatin, a pyrrolidone non-competitive inhibitor of hydroxymethyl-glutaryl coenzyme A (HMG-CoA) reductase.

(Crilvastatin 1S, NCI Thesaurus)

Atorvastatin competitively inhibits hepatic hydroxymethyl-glutaryl coenzyme A (HMG-CoA) reductase, the enzyme which catalyzes the conversion of HMG-CoA to mevalonate, a key step in cholesterol synthesis.

(Atorvastatin, NCI Thesaurus)

Cerivastatin competitively inhibits hepatic hydroxymethyl-glutaryl coenzyme A (HMG-CoA) reductase, the enzyme which catalyzes the conversion of HMG-CoA to mevalonate, a key step in cholesterol synthesis.

(Cerivastatin, NCI Thesaurus)




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