| / English Dictionary |
COLLAGEN
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
A fibrous scleroprotein in bone and cartilage and tendon and other connective tissue; yields gelatin on boiling
Classified under:
Hypernyms ("collagen" is a kind of...):
albuminoid; scleroprotein (a simple protein found in horny and cartilaginous tissues and in the lens of the eye)
Holonyms ("collagen" is a substance of...):
bone; os (rigid connective tissue that makes up the skeleton of vertebrates)
connective tissue (tissue of mesodermal origin consisting of e.g. collagen fibroblasts and fatty cells; supports organs and fills spaces between them and forms tendons and ligaments)
cartilage; gristle (tough elastic tissue; mostly converted to bone in adults)
sinew; tendon (a cord or band of inelastic tissue connecting a muscle with its bony attachment)
Derivation:
collagenic; collagenous (relating to or consisting of collagen)
Context examples:
This allele, which encodes collagen alpha-1(XI) chain protein, plays a role in modulation of cartilage structure.
(COL11A1 wt Allele, NCI Thesaurus)
An injectable collagen matrix gel containing the antimetabolite methotrexate and the sympathicomimetic agent epinephrine with potential antineoplastic activity.
(Methotrexate-E Therapeutic Implant, NCI Thesaurus)
A subtype of classical Hodgkin lymphoma characterized by collagen bands surrounding lymphoid nodules.
(Nodular Sclerosis Classical Hodgkin Lymphoma, NCI Thesaurus/WHO)
Cathepsin K, a tissue-specific cysteine protease that catalyzes degradation of bone matrix proteins such as collagen I/II, elastin, and osteonectin plays an important role in osteoclast function and bone resorption.
(Odanacatib, NCI Thesaurus)
This allele, which encodes platelet endothelial cell adhesion molecule protein, plays a role in transendothelial migration of leukocytes, angiogenesis, integrin activation, and may inhibit platelet-collagen interactions.
(PECAM1 wt Allele, NCI Thesaurus)
Attachment is improved by using collagen coated flasks.
(PC-12, NCI Thesaurus)
It is characterized by the formation of dense collagen tissue and reactive bone.
(Periosteal Desmoid Tumor, NCI Thesaurus)
This agent also inhibits DNA synthesis and the production of mRNA for collagen types I and III, resulting in a reduction in radiation-induced fibrosis.
(Pirfenidone, NCI Thesaurus)
The determination of the collagen closure time, as a surrogate of platelet function, present in a sample.
(Platelet Function Closure Time Measurement, NCI Thesaurus)
It is composed of thin collagen fibers.
(Papillary dermis, NCI Thesaurus)
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