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COPOLYMER

Pronunciation (US): Play  (GB): Play

 I. (noun) 

Sense 1

Meaning:

A polymer consisting of two or more different monomersplay

Classified under:

Nouns denoting substances

Hypernyms ("copolymer" is a kind of...):

polymer (a naturally occurring or synthetic compound consisting of large molecules made up of a linked series of repeated simple monomers)

Derivation:

copolymerise; copolymerize (polymerize together)

Credits

 Context examples: 

Several different classes and types of copolymers exist.

(Copolymerization, NCI Thesaurus)

The copolymer residue increases the water-solubility of paclitaxel and allows delivery of higher doses than those achievable with paclitaxel alone.

(Paclitaxel-loaded polymeric micelle, NCI Thesaurus)

Carbetimer (carboxyimamidate) is a low molecular weight derivatized copolymer of ethylene and maleic anhydride.

(Carbetimer, NCI Thesaurus)

A hydrochloride salt form of colestipol, a positively charged, non-digestible, triamine and epoxypropane copolymer anion-exchange resin that binds to bile acids in the intestine to form an insoluble complex, which is excreted in the feces.

(Colestipol Hydrochloride, NCI Thesaurus)

A synthetic polymer (copolymer of 1,3-bis(methylaminocarboxyl)-2-methylenepropanecarbamate and N-vinyl pyrrolidone) of low molecular weight which acts as a nonspecific immune modulator and has been shown to have significant antitumor activity in vitro and in vivo in preclinical and some early clinical studies.

(Copovithane, NCI Thesaurus)

A biodegradable poly(ethylene glycol)-poly(D,L-lactide) copolymer micelle nanoparticle-entrapped formulation of paclitaxel with antineoplastic activity.

(Paclitaxel-loaded polymeric micelle, NCI Thesaurus)

The thermosensitive triblock copolymer component of this formulation transforms from a water-soluble polymer at room temperature to a water-insoluble, biodegradable gel depot at body temperature; intratumoral controlled-release of paclitaxel from the gel minimizes systemic exposure to paclitaxel and the paclitaxel toxicity profile.

(PGLA/PEG Copolymer-Based Paclitaxel, NCI Thesaurus)

Upon intratumoral injection, paclitaxel is released slowly and continuously into tumor tissues from the gelled thermosensitive triblock copolymer over a period of 4 to 6 weeks; in tumor cells, paclitaxel binds to tubulin and inhibits the disassembly-assembly dynamics of microtubules, resulting in cell cycle arrest and cell death.

(PGLA/PEG Copolymer-Based Paclitaxel, NCI Thesaurus)




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