| / English Dictionary |
CORTISOL
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
An adrenal-cortex hormone (trade names Hydrocortone or Cortef) that is active in carbohydrate and protein metabolism
Synonyms:
Cortef; cortisol; hydrocortisone; Hydrocortone
Classified under:
Hypernyms ("cortisol" is a kind of...):
adrenal cortical steroid; corticoid; corticosteroid (a steroid hormone produced by the adrenal cortex or synthesized; administered as drugs they reduce swelling and decrease the body's immune response)
Context examples:
The determination of the amount of free, unbound cortisol present in a sample.
(Free Cortisol Measurement, NCI Thesaurus)
Mutations in the gene are a primary cause of glucocorticoid resistance, or cortisol resistance.
(NR3C1 wt Allele, NCI Thesaurus)
This allele, which encodes cytochrome P450 11B1, mitochondrial protein, plays a role in the conversion of progesterone to cortisol in the adrenal cortex.
(CYP11B1 wt Allele, NCI Thesaurus)
Your treatment will depend on why you have too much cortisol.
(Cushing's Syndrome, NIH: National Institute of Diabetes and Digestive and Kidney Diseases)
A group of syndromes caused by inherited defects in cortisol (HYDROCORTISONE) and/or ALDOSTERONE biosynthesis.
(Congenital Adrenal Gland Hyperplasia, NLM, Medical Subject Headings)
Cushing’s syndrome may be caused by tumors of the adrenal glands or other parts of the body that produce excess cortisol.
(Children with Cushing syndrome may have higher suicide risk, NIH)
They examined the effect of recalling positive memories on two signs of vulnerability to depression: negative self-related thoughts and high morning levels of the stress hormone cortisol.
(Recalling happy memories during adolescence can reduce risk of depression, University of Cambridge)
Cortisol is involved in the fight-or-flight response and binds to GRs and MRs in different tissues of the body to reduce inflammation, among other functions.
(Healthy hearts need two proteins working together, National Institutes of Health)
A hormone secreted by the anterior portion of the pituitary gland and regulates hormone, primarily cortisol, secreted by the adrenal gland.
(Adrenocorticotropic hormone, NCI Thesaurus)
A disorder that occurs when the adrenal cortex does not produce enough of the hormone cortisol and in some cases, the hormone aldosterone.
(Adrenal Gland Insufficiency, NCI Thesaurus/CTCAE)
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