| / English Dictionary |
COVALENT
| Pronunciation (US): |  | (GB): | |
I. (adjective)
Sense 1
Meaning:
Of or relating to or characterized by covalence
Example:
covalent bond
Classified under:
Relational adjectives (pertainyms)
Pertainym:
covalence (valence characterized by the sharing of electrons in a chemical compound; the number of pairs of electrons an atom can share)
Derivation:
covalence; covalency (valence characterized by the sharing of electrons in a chemical compound; the number of pairs of electrons an atom can share)
Context examples:
Plasminogen Activator Interaction involves temporary non-covalent binding through intermolecular physical forces of attraction with heterogeneous group of widely expressed lysosomal and secreted serine proteases having fibrin-binding activity that convert plasminogen to fibrinolytic plasmin.
(Plasminogen Activator Interaction, NCI Thesaurus)
A covalent conjugate of recombinant interferon alpha and polyethylene glycol (PEG), used as an antiviral and antineoplastic agent.
(Pegylated Interferon Alfa, NCI Thesaurus)
A covalent conjugate of recombinant interferon alfa, subtype 2a, and polyethylene glycol (PEG), used as an antiviral and antineoplastic agent.
(Peginterferon alfa-2a, NCI Thesaurus)
Orlistat forms a covalent bond with the active serine site in gastric and pancreatic lipases, thereby inhibiting their activity and preventing dietary fat from being hydrolyzed and absorbed.
(Orlistat, NCI Thesaurus)
A process that involves the non-covalent binding of parathyroid hormone to one of the parathyroid hormone receptors.
(Parathyroid Hormone Receptor Binding, NCI Thesaurus)
BAY 56-3722 stabilizes the topoisomerase I-DNA covalent complex and forms an enzyme-drug-DNA ternary complex.
(BAY 56-3722, NCI Thesaurus)
Immunoglobulin-like neuronal surface glycoprotein which binds to a variety of other cell adhesion proteins to mediate adhesion, guidance, and differentiation during neuronal growth; may contain covalent phospholipid.
(CD56 Antigen, NIH CRISP Thesaurus)
Acetate salt of Ametantrone, a topoisomerase II inhibitor of the anthrapyrazole family that causes covalent cross-links in DNA.
(Ametantrone Acetate, NCI Thesaurus)
After internalization and proteolytic cleavage, SN-38 selectively stabilizes topoisomerase I-DNA covalent complexes, resulting in DNA breaks that inhibit DNA replication and trigger apoptosis.
(Anti-TROP-2 Antibody-Drug Conjugate IMMU-132, NCI Thesaurus)
A topoisomerase II inhibitor of the anthrapyrazole family that causes covalent cross-links in DNA of tumor cells.
(Ametantrone, NCI Thesaurus)
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