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CROSS-LINKAGE

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 I. (noun) 

Sense 1

Meaning:

A side bond that links two adjacent chains of atoms in a complex moleculeplay

Synonyms:

cross-link; cross-linkage

Classified under:

Nouns denoting natural phenomena

Hypernyms ("cross-linkage" is a kind of...):

bond; chemical bond (an electrical force linking atoms)

Derivation:

cross-link (join by creating covalent bonds (of adjacent chains of a polymer or protein))

Credits

 Context examples: 

This inactivation prevents the formation of the cross-linkage of peptidoglycan strands, thereby inhibiting the third and last stage of bacterial cell wall synthesis.

(Carbenicillin Indanyl Sodium, NCI Thesaurus)

This inactivation prevents the cross-linkage of peptidoglycan strands, thereby inhibiting the third and last stage of bacterial cell wall synthesis.

(Carbenicillin, NCI Thesaurus)

Carbenicillin binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall, thereby preventing the cross-linkage of peptidoglycans, which are critical components of the bacterial cell wall.

(Carbenicillin Potassium, NCI Thesaurus)

An aziridinyl-substituted cyclophosphazene and a putrescence derivative that may cause DNA cross-linkage.

(AZP, NCI Thesaurus)

Azlocillin binds to penicillin-binding proteins (PBPs) located inside the bacterial cell wall, thereby inhibiting the cross-linkage of peptidoglycans, which are critical components of the bacterial cell wall.

(Azlocillin Sodium, NCI Thesaurus)

Methicillin binds to specific penicillin-binding proteins (BPBs) on the bacterial cell wall, thereby preventing the cross-linkage of peptidoglycans, which are critical components of the bacterial cell wall.

(Methicillin, NCI Thesaurus)

Ampicillin binds to and inactivated penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall, thereby preventing the cross-linkage of peptidoglycans, which are critical components of the bacterial cell wall.

(Hetacillin Potassium, NCI Thesaurus)

Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity.

(Amdinocillin, NCI Thesaurus)

Apalcillin specifically binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall, thereby preventing the cross-linkage of peptidoglycans, which are critical components of the bacterial cell wall.

(Apalcillin, NCI Thesaurus)

Following absorption, carbenicillin phenyl sodium is rapidly hydrolyzed to the active carbenicillin, which binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall, thereby preventing the cross-linkage of peptidoglycans, which are critical components of the bacterial cell wall.

(Carbenicillin Phenyl, NCI Thesaurus)




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