CYTOSKELETON

Pronunciation (US): (GB):

Meaning:

A microscopic network of actin filaments and microtubules in the cytoplasm of many living cells that gives the cell shape and coherence

Classified under:

Nouns denoting body parts

Hypernyms ("cytoskeleton" is a kind of...):

anatomical structure; bodily structure; body structure; complex body part; structure (a particular complex anatomical part of a living thing and its construction and arrangement)

Holonyms ("cytoskeleton" is a part of...):

cytol; cytoplasm (the protoplasm of a cell excluding the nucleus; is full of proteins that control cell metabolism)

Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulin.

(Microtubule, NCI Thesaurus/LocusLink)

This gene plays a role in both cell adhesion and cytoskeleton modeling.

(MSN Gene, NCI Thesaurus)

This protein plays a role in both cell adhesion and connection of the cytoskeleton to the plasma membrane.

(Moesin, NCI Thesaurus)

Microfilaments physically associate with microtubules to play a structural role in cytoskeleton integrity.

(Microfilament Protein, NCI Thesaurus)

A fluid cytoplasmic substance filling the interstices of the cytoskeleton.

(Cytoplasmic Matrix, NCI Thesaurus)

This allele, which encodes moesin protein, is involved in the modulation both of cell-cell adhesion and the structure of the cytoskeleton.

(MSN wt Allele, NCI Thesaurus)

This protein plays a role in cytoskeleton rearrangement andmetastasis suppression.

(Metastasis-Suppressor KiSS-1, NCI Thesaurus)

Calpains digest the links between the actin cytoskeleton and several focal adhesion complex proteins; talin, paxillin and focal adhesion kinase.

(Calpain-2 Cell Motility Pathway, NCI Thesaurus/BIOCARTA)

The classical cadherins have five homologous extracellular domains and a cytosolic domain which binds through catenin to the cytoskeleton.

(Cadherin, NCI Thesaurus)

This allele, which encodes PDZ and LIM domain protein 4, may play a role in the modulation of the structure of the actin cytoskeleton.

(PDLIM4 wt Allele, NCI Thesaurus)