| / English Dictionary |
CYTOSOL
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
The aqueous part of the cytoplasm within which various particles and organelles are suspended
Classified under:
Hypernyms ("cytosol" is a kind of...):
cytol; cytoplasm (the protoplasm of a cell excluding the nucleus; is full of proteins that control cell metabolism)
Context examples:
This lymphokine and the JAB1 protein form a complex in the cytosol near the peripheral plasma membrane, which may indicate an additional role in integrin signaling pathways.
(Macrophage Migration Inhibitory Factor, NCI Thesaurus)
Liposome encapsulation of this agent promotes efficient drug delivery into the cytosol from the endosome compartment of the cell.
(liposome-encapsulated irinotecan hydrochloride PEP02, NCI Thesaurus)
This complex is expressed in the cytosol of neutrophils and macrophages and plays a role in multiple host defense related processes including immunomodulation, neutrophil chemotaxis and both antibacterial and antifungal responses.
(Calprotectin, NCI Thesaurus)
Any process that involves the local flux of calcium from the endoplasmic reticulum or sarcoplasmic reticulum to the cytosol.
(Calcium Signaling, NCI Thesaurus)
Found only in the cytosol, TP53BP2 impedes cell cycle progression beyond G2/M.
(Apoptosis-Stimulating of p53 Protein 2, NCI Thesaurus)
Inactive Nrf2 is retained in the cytosol by association a complex with the cytoskeletal protein Keap1.
(Oxidative Stress Pathway, NCI Thesaurus/BIOCARTA)
Matrix proteins in the cytosol are recognized by peroxisomal targeting signals (PTS) and transported to the docking complex at the peroxisomal membrane.
(Peroxisome Biogenesis Pathway, NCI Thesaurus/KEGG)
Wave-1 is held in an inactive complex in the cytosol that is activated to allow Wave-1 to associate with Arp2/3.
(Actin Branching Pathway, NCI Thesaurus/BIOCARTA)
It could be involved in the transport of heme from the mitochondria to the cytosol.
(ATP-Binding Cassette, Sub-Family B, Member 6, NCI Thesaurus)
After subcutaneous injection of the autologous tumor cell proteoliposomes chronic lymphocytic leukemia vaccine, liposomes deliver the encapsulated tumor antigens into the cytosol of antigen presenting cells (APCs).
(Autologous Tumor Cell Proteoliposome Chronic Lymphocytic Leukemia Vaccine, NCI Thesaurus)
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