| / English Dictionary |
DC
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
The district occupied entirely by the city of Washington; chosen by George Washington as the site of the capital of the United States and created out of land ceded by Maryland and Virginia
Synonyms:
D.C.; DC; District of Columbia
Classified under:
Nouns denoting spatial position
Instance hypernyms:
federal district (a district set apart as the seat of government of a federation)
Meronyms (parts of "DC"):
American capital; capital of the United States; Washington; Washington D.C. (the capital of the United States in the District of Columbia and a tourist mecca; George Washington commissioned Charles L'Enfant to lay out the city in 1791)
Holonyms ("DC" is a part of...):
America; the States; U.S.; U.S.A.; United States; United States of America; US; USA (North American republic containing 50 states - 48 conterminous states in North America plus Alaska in northwest North America and the Hawaiian Islands in the Pacific Ocean; achieved independence in 1776)
Sense 2
Meaning:
An electric current that flows in one direction steadily
Synonyms:
DC; direct current; direct electric current
Classified under:
Nouns denoting natural phenomena
Hypernyms ("DC" is a kind of...):
electrical energy; electricity; power (energy made available by the flow of electric charge through a conductor)
Context examples:
Flt3L stimulates both the proliferation of dendritic cells (DCs) and their migration to the tumor site.
(Ad-hCMV-Flt3L, NCI Thesaurus)
The CD40L moiety part of the fusion protein binds to CD40 receptors on dendritic cells (DCs).
(Ad-sig-hMUC-1/ecdCD40L Vaccine, NCI Thesaurus)
Exosomes derived from autologous maturing dendritic cells (DCs) are pulsed with HLA-DP04-restricted MAGE-3, and HLA-A02-restricted peptides NY-ESO-1, MAGE-1, MAGE-3, and MART-1.
(NSCLC Antigen-Loaded Dendritic Cell-derived Exosomes, NCI Thesaurus)
Autologous dendritic cells (DCs) transduced with the replication-deficient adenoviral vector Ad5F53 encoding the Epstein-Barr virus (EBV) transmembrane latent membrane proteins 1 and 2 (LMP1/LMP2) with potential immunostimulatory activity.
(Ad5F35-LMP1/LMP2-Transduced Autologous Dendritic Cells, NCI Thesaurus)
A cancer vaccine comprised of autologous dendritic cells (DCs) pulsed with the marine sponge glycolipid alpha-galactosylceramide (alpha-GalCer) with potential immunostimulatory and antimetastatic activities.
(Alpha-Galactosylceramide-Pulsed Autologous Dendritic Cells, NCI Thesaurus)
Upon intratumoral administration of the allogeneic dendritic cell vaccine COMBIG-DC, these activated DCs attract natural killer (NK) cells, induce an anti-inflammatory response leading to the induction of NK-cell-mediated tumor cell death.
(Allogeneic Dendritic Cell Vaccine COMBIG-DC, NCI Thesaurus)
A cell-based cancer vaccine consisting of autologous dendritic cells (DCs) pulsed with mesothelioma tumor lysate with potential immunostimulating and antineoplastic activities.
(Mesothelioma Tumor Lysate-Pulsed Autologous Dendritic Cell Vaccine, NCI Thesaurus)
Therefore, alphaDC1 has a much more significant capability of inducing helper T cell (CD4+ T-cell) responses in comparison with the "gold standard" DCs.
(Alpha-type-1 Polarized Dendritic Cells, NCI Thesaurus)
This ultimately leads to the proliferation of human B cells, activation of natural killer (NK) cells and dendritic cells (DCs), an increase in HLA-I and HLA-II expression and activation of CD8-lymphocytes.
(Multi-subtype Natural Human Leukocyte Interferon Alpha, NCI Thesaurus)
A cell-based cancer vaccine composed of autologous dendritic cells (DCs) transduced with a replication-deficient adenovirus vector encoding HER-2 with potential antineoplastic activity.
(Adenovirus HER2-Transduced Autologous Dendritic Cell Vaccine, NCI Thesaurus)
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