| / English Dictionary |
DEMONSTRATED
| Pronunciation (US): |  | (GB): | |
I. (adjective)
Sense 1
Meaning:
Having been demonstrated or verified beyond doubt
Classified under:
Similar:
incontestable; incontestible (incapable of being contested or disputed)
II. (verb)
Sense 1
Past simple / past participle of the verb demonstrate
Context examples:
What we have demonstrated is that, by regulating this particular interaction, the evolution is decreased, and it also brings the condition to a lighter state, Ferreira said.
(Molecule created in Brazil helps fight heart failure, Agência Brasil)
Xie et al. demonstrated that Plk3, like Chk1 and Chk2, also phosphorylates Cdc25C on serine-216 contributing to cell cycle arrest.
(Cell Cycle Progression Pathway, NCI Thesaurus/BIOCARTA)
It has been demonstrated that PKA-RIIa dissociates and redistributes from centrosomes at mitosis.
(Centrosome Pathway, NCI Thesaurus/BIOCARTA)
The importance of this pathway in both growth control and development has been demonstrated via the transforming properties of various mutant forms of Ras, Raf, and MEK and by their effects on development.
(Erk1/Erk2 MAPK Signaling Pathway, NCI Thesaurus/BIOCARTA)
Dofequidar has demonstrated reversal of the MDR phenotype in those cells exposed to various chemotherapeutic agents, such as vinca alkaloids and anthracyclines.
(Dofequidar Fumarate, NCI Thesaurus)
A human nuclear matrix protein with demonstrated immunohistochemical staining differences between benign and malignant prostate tissue.
(Nucleophosmin, NCI Thesaurus)
More recently it has been demonstrated that Pelp1 mediates the interaction of ER and Src leading to the activation of the Mitogen Activated Protein Kinases Erk1 and Erk2.
(Pelp1 Estrogen Receptor Pathway, NCI Thesaurus/BIOCARTA)
In a study using endothelial cells it was demonstrated that S1P induces activation of alpha-v and B3 integrins via RhoA.
(Phospholipid Signaling Pathway, NCI Thesaurus/BIOCARTA)
Further, it has been demonstrated to have an inhibitory effect on non-small-cell lung cancer development and is currently being investigated as a prognostic biomarker for the disease.
(DNAJB4 wt Allele, NCI Thesaurus)
DHA-paclitaxel exhibits improved pharmacokinetic and toxicity profiles when compared to conventional paclitaxel and has demonstrated antineoplastic activity in animal models of cancer.
(DHA-paclitaxel, NCI Thesaurus)
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