/ English Dictionary

DISRUPT

Pronunciation (US):

(GB):

 I. (verb) 

Sense 1

Meaning:

Interfere in someone else's activity

Example:

Please don't interrupt me while I'm on the phone

Synonyms:

disrupt; interrupt

Classified under:

Verbs of size, temperature change, intensifying, etc.

Hypernyms (to "disrupt" is one way to...):

barge in; break in; butt in; chime in; chisel in; cut in; put in (break into a conversation)

Troponyms (each of the following is one way to "disrupt"):

cut in (interrupt a dancing couple in order to take one of them as one's own partner)

cut short (cause to end earlier than intended)

Sentence frames:

Somebody ----s something
Somebody ----s somebody

Derivation:

disruption (an act of delaying or interrupting the continuity)

Sense 2

Meaning:

Throw into disorder

Example:

This event disrupted the orderly process

Classified under:

Verbs of size, temperature change, intensifying, etc.

Sentence frames:

Somebody ----s something
Somebody ----s somebody
Something ----s somebody
Something ----s something

Derivation:

disruption (the act of causing disorder)

disruptive (characterized by unrest or disorder or insubordination)

Sense 3

Meaning:

Make a break in

Example:

We interrupt the program for the following messages

Synonyms:

break up; cut off; disrupt; interrupt

Classified under:

Verbs of telling, asking, ordering, singing

Hypernyms (to "disrupt" is one way to...):

break; break off; discontinue; stop (prevent completion)

Troponyms (each of the following is one way to "disrupt"):

cut; cut off (cease, stop)

punctuate (interrupt periodically)

break (interrupt the flow of current in)

put aside; put away (turn away from and put aside, perhaps temporarily)

break; intermit; pause (cease an action temporarily)

barge in; break in; butt in; chime in; chisel in; cut in; put in (break into a conversation)

burst in on; burst upon (spring suddenly)

heckle (challenge aggressively)

come in; inject; interject; interpose; put in; throw in (to insert between other elements)

block; jam (interfere with or prevent the reception of signals)

stop; stop over (interrupt a trip)

take off; take time off (take time off from work; stop working temporarily)

Sentence frames:

Somebody ----s
Somebody ----s something
Somebody ----s somebody
Something ----s somebody
Something ----s something

Derivation:

disruption (an act of delaying or interrupting the continuity)

Credits

 Context examples: 

This agent also disrupts tumor neovascularization, reducing tumor blood flow and so inducing a cytotoxic effect.

(ABT-751, NCI Thesaurus)

A metabolic disorder occurs when abnormal chemical reactions in your body disrupt this process.

(Metabolic Disorders, NIH)

Aminothiadiazole competitively inhibits inosine 5-monophosphate dehydrogenase, thereby disrupting the regulation of cell proliferation and differentiation in a number of cells.

(Aminothiadiazole, NCI Thesaurus)

Ansamitomicin P-3 binds to tubulin at the maytansine-binding site, thereby inhibiting microtubule assembly, inducing microtubule disassembly, and disrupting mitosis.

(Ansamitomicin P-3, NCI Thesaurus)

Nitration may target neurofilament proteins, disrupting their phosphorylation and affecting axonal transport.

(Amyotrophic Lateral Sclerosis Pathway, NCI Thesaurus/KEGG)

GRKs attenuate GPCR signaling in concert with arrestins, proteins that bind GRK-phosphorylated GPCRs to disrupt interaction with G-protein and to terminate signaling.

(Attenuation of GPCR Signaling Pathway, NCI Thesaurus/BIOCARTA)

This agent is also incorporated into RNA, thereby disrupting normal RNA function and impairing tRNA cytosine-5-methyltransferase activity.

(Azacitidine, NCI Thesaurus)

MET inhibitor EMD 1204831 selectively binds to Met tyrosine kinase, thereby disrupting MET mediated signal transduction pathways.

(MET Tyrosine Kinase Inhibitor EMD 1204831, NCI Thesaurus)

The ricin A chain component binds to B-cells and disrupts ribosomal activity and protein synthesis and induces cell cycle arrest.

(Monoclonal Antibody HD37-SMPT-dgA Immunotoxin, NCI Thesaurus)

MET tyrosine kinase inhibitor EMD 1214063 selectively binds to MET tyrosine kinase and disrupts MET signal transduction pathways, which may induce apoptosis in tumor cells overexpressing this kinase.

(MET Tyrosine Kinase Inhibitor EMD 1214063, NCI Thesaurus)

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