DISTAL

Pronunciation (US): (GB):

I. (adjective)

Sense 1

Meaning:

Situated farthest from point of attachment or origin, as of a limb or bone

Classified under:

Adjectives

Domain category:

anatomy; general anatomy (the branch of morphology that deals with the structure of animals)

Antonym:

proximal (situated nearest to point of attachment or origin)

Sense 2

Meaning:

Directed away from the midline or mesial plane of the body

Classified under:

Adjectives

Similar:

lateral (lying away from the median and sagittal plane of a body)

Domain category:

anatomy; general anatomy (the branch of morphology that deals with the structure of animals)

Antonym:

mesial (being in or directed toward the midline or mesial plane of the body)

Credits

Context examples:

The region distal to the z-line of the gastroesophageal junctions, the area where the esophagus attaches to the stomach.

(Cardia Orifice, NCI Thesaurus)

Solitary or multiple foci of increased cellularity distal to terminal bronchioles.

(Alveoli Epithelial Hyperplasia of the Mouse Pulmonary System, NCI Thesaurus/MMHCC)

The frequency of distal metastases is low.

(Ameloblastic Fibrosarcoma, NCI Thesaurus)

The most common clinical presentation is a symmetric distal mixed sensorimotor polyneuropathy.

(Paraneoplastic Polyneuropathy, NLM, Medical Subject Headings)

Squamous cell carcinomas that affect or cross the junction of the stomach and esophagus are classified as carcinomas of the distal esophagus.

(Adenocarcinoma of the Gastroesophageal Junction, NCI Thesaurus)

The upper distal process of the scapula.

(Acromion, NCI Thesaurus)

Reddening of the palmar and plantar regions of the body with occasional involvement of the distal extremities.

(Acral Erythema, NCI Thesaurus)

It often involves the long bones (particularly distal femur, proximal tibia, and proximal humerus).

(Osteosarcoma, NCI Thesaurus)

The cutaneous plate on the dorsal surface of the distal end of a finger or toe.

(Nail, NCI Thesaurus)

Expressed in hepatocytes and kidney distal/proximal tubules, secreted 644-aa isoform 2 may bind semaphorins and induce apoptosis by sequestering VEGF-165; it has an adverse effect on blood vessel integrity.