| / English Dictionary |
DYSFUNCTION
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
(medicine) any disturbance in the functioning of an organ or body part or a disturbance in the functioning of a social group
Example:
sexual relationship dysfunction
Synonyms:
Classified under:
Nouns denoting stable states of affairs
Hypernyms ("dysfunction" is a kind of...):
pathology (any deviation from a healthy or normal condition)
Domain category:
medical specialty; medicine (the branches of medical science that deal with nonsurgical techniques)
Hyponyms (each of the following is a kind of "dysfunction"):
ED; erectile dysfunction; male erecticle dysfunction (impotence resulting from a man's inability to have or maintain an erection of his penis)
palsy; paralysis (loss of the ability to move a body part)
Derivation:
dysfunctional (impaired in function; especially of a bodily system or organ)
Context examples:
It is characterized by ventricular arrhythmia and right ventricular dysfunction.
(Arrhythmogenic Right Ventricular Dysplasia, NCI Thesaurus)
Without clinical signs or indications that raise the possibility of a particular disorder or dysfunction.
(Asymptomatic, NCI Thesaurus)
C3orf27 gene dysfunction is associated with several types of cancer including acute myeloid monocytic leukemia and colorectal cancer.
(C3orf27 wt Allele, NCI Thesaurus)
Psychosis is associated with dopamine system dysfunction, characterized by greater dopamine release and synthesis capacity in the striatum.
(Neuromelanin-sensitive MRI identified as a potential biomarker for psychosis, National Institutes of Health)
The disorders are characterized by muscle dysfunction.
(Metabolic Myopathy, NCI Thesaurus)
Mitochondrial Damage involves any process that leads to dysfunction of mitochondria, whether by oxidative damage, mutation of mitochondrial DNA or other by means.
(Mitochondrial Damage, NCI Thesaurus)
Mutations and dysfunction in the gene is associated with obesity.
(NR0B2 wt Allele, NCI Thesaurus)
The current paradigm suggests that the heart adapts to excess of hemodynamic loading by compensatory hypertrophy, which under condition of persistent stress, over time evolves into dysfunction and myocardial failure.
(NFAT Pathway, NCI Thesaurus/BIOCARTA)
Relevant elements of medical history, including preexisting medical conditions, events and facts (e.g., allergies, race, pregnancy, smoking and alcohol use, hepatic/renal dysfunction, etc.) not listed in MedWatch form.
(Other Personal Medical History, NCI Thesaurus)
Mutations or altered expression of these proteins contributes to PD pathogenesis through common mechanisms that result in proteasome dysfunction, mitochondrial impairment, and oxidative stress.
(Parkinson's Disease Pathway KEGG, NCI Thesaurus/KEGG)
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