| / English Dictionary |
ENANTIOMER
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
Either one of a pair of compounds (crystals or molecules) that are mirror images on each other but are not identical
Synonyms:
enantiomer; enantiomorph
Classified under:
Hypernyms ("enantiomer" is a kind of...):
chemical compound; compound ((chemistry) a substance formed by chemical union of two or more elements or ingredients in definite proportion by weight)
Context examples:
A liposomal nanoparticle-based therapeutic vaccine composed of the cationic lipid R-DOTAP (R-enantiomer of 1,2-dioleoyl-3-trimethylammonium-propane chloride) encapsulating six human papillomavirus 16 (HPV-16) E6 and E7 peptides, with potential immunostimulating activity.
(Liposomal HPV-16 E6/E7 Multipeptide Vaccine PDS0101, NCI Thesaurus)
The R-enantiomer of the racemic synthetic agent modafinil with central nervous system (CNS) stimulant and wakefulness-promoting activities.
(Armodafinil, NCI Thesaurus)
In addition, both enantiomers of carvedilol bind to and block alpha 1-adrenergic receptors, thereby causing vasodilation and reducing peripheral vascular resistance.
(Carvedilol phosphate, NCI Thesaurus)
The R-enantiomer of the calcium channel blocker verapamil.
(Dexverapamil, NCI Thesaurus)
The oxalate salt of escitalopram, a pure S-enantiomer of the racemic bicyclic phthalane derivative citalopram, with antidepressant activity.
(Escitalopram Oxalate, NCI Thesaurus)
The levo-enantiomer of an orally bioavailable polyphenolic aldehyde, derived primarily from unrefined cottonseed oil, with potential antineoplastic activity.
(L-Gossypol, NCI Thesaurus)
A synthetic antihypertensive methoxyphenoxy- 2-propanol derivative with no intrinsic sympathomimetic activity, Carvedilol acts as a nonselective beta-adrenoceptor blocking agent (S(-) enantiomer) and as an alpha 1-adrenoceptor blocker (R(+) and S(-) enantiomers).
(Carvedilol, NCI Thesaurus)
Carvedilol is a racemic mixture; the S(-) enantiomer non-selectively binds to and blocks beta-adrenergic receptors, exerting negative inotropic and chronotropic effects, leading to a reduction in cardiac output.
(Carvedilol Phosphate Extended-Release Capsule, NCI Thesaurus)
The S enantiomer of carvedilol nonselectively binds to and blocks beta-adrenergic receptors, thereby exerting negative inotropic and chronotropic effects, and leading to a reduction in cardiac output.
(Carvedilol phosphate, NCI Thesaurus)
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