| / English Dictionary |
ENDOTHELIAL
| Pronunciation (US): |  | (GB): | |
I. (adjective)
Sense 1
Meaning:
Of or relating to or located in the endothelium
Classified under:
Relational adjectives (pertainyms)
Pertainym:
endothelium (an epithelium of mesoblastic origin; a thin layer of flattened cells that lines the inside of some body cavities)
Derivation:
endothelium (an epithelium of mesoblastic origin; a thin layer of flattened cells that lines the inside of some body cavities)
Context examples:
The diagnosis also depends on findings of tumor necrosis, and vascular endothelial proliferation.
(Mouse Glioblastoma, NCI Thesaurus/MMHCC)
Multikinase inhibitor 4SC-203 selectively inhibits FMS-related tyrosine kinase 3 (FLT3/STK1), FLT3 mutated forms, and vascular endothelial growth factor receptors (VEGFRs).
(Multikinase Inhibitor 4SC-203, NCI Thesaurus)
PECAM-1 mediates the migration of monocytes and other immune cells into inflamed tissues through interaction with vascular endothelial cells.
(Monocyte Phagocytosis and Adhesion Pathway, NCI Thesaurus/BIOCARTA)
CCR4, a G-coupled-protein receptor for C-C chemokines such MIP-1, RANTES, TARC and MCP-1, is expressed on the surfaces of some types of T cells, endothelial cells, and some types of neurons.
(Mogamulizumab, NCI Thesaurus)
A humanized monoclonal antibody directed against vascular endothelial growth factor (VEGF), a pro-angiogenic cytokine.
(Monoclonal Antibody HuMV833, NCI Thesaurus)
An alpha(v)beta integrin inhibitor blocks the activity of an endothelial cell-surface expressed alpha(v)integrin, thereby inhibiting endothelial cell-cell interactions, endothelial cell-matrix interactions, and angiogenesis.
(Alpha V Beta Inhibitor, NCI Thesaurus)
Blockade of IL-1 activity may inhibit the cascade of downstream pro-angiogenic factors such as vascular endothelial cell growth factor, tumor necrosis factor-alpha, and IL-6, resulting in inhibition of tumor angiogenesis.
(Anakinra, NCI Thesaurus)
Each of these lymphocyte adhesion molecules interacts with specific ligands expressed on cells like endothelial cells to moderate adhesion between cells.
(Adhesion Molecules on Lymphocyte Pathway, NCI Thesaurus/BIOCARTA)
The expressed endostatin may inhibit endothelial cell proliferation and angiogenesis which may result in a reduction of tumor growth.
(Adenovirus Encoding Recombinant Human Endostatin, NCI Thesaurus)
The astrocytic endfeet release molecules that regulate the tight junctions between the endothelial cells.
(Brain tumor invasion along blood vessels may lead to new cancer treatments, NIH)
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