| / English Dictionary |
ENDPOINT
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
A place where something ends or is complete
Synonyms:
end point; endpoint; termination; terminus
Classified under:
Nouns denoting spatial position
Hypernyms ("endpoint" is a kind of...):
end; terminal (either extremity of something that has length)
Context examples:
The amino acids alanine, glycine, serine, cysteine, tryptophan and threonine all have a common endpoint, the metabolic intermediate pyruvate.
(Catabolic Pathways for Alanine, Glycine, Serine, Cysteine, Tryptophan, and Threonine, NCI Thesaurus/BIOCARTA)
Method allows to maintain steady state plasma/serum medication levels, a smaller total daily dose of drug to achieve the same pharmacodynamic endpoint in comparison with intermittent or bolus infusion, and may result in lower toxicity.
(Continuous Intravenous Infusion, NCI Thesaurus)
The Biostatistics Shared Resource works with Cancer Center investigators to define study/protocol objectives and endpoints, analyze pilot data, select an appropriate study design, blinding methods and randomization scheme, plan interim analyses, define an adequate sample size and accrual rate, develop and evaluate the statistical methods and analyse data, prepare statistical sections of the grant and protocol applications, analyze and design relational databases, forms and reports.
(Biostatistics Shared Resource, NCI Thesaurus)
The design of the study (such as a case report for an individual patient or a randomized double-blinded controlled clinical trial) and the endpoints measured (such as survival or quality of life) affect the strength of the evidence.
(Levels of evidence, NCI Dictionary)
Clinical endpoints are the most credible characteristics used in the assessment of the benefits and risks of a therapeutic intervention in randomized clinical trials.
(Clinical Endpoint, NCI Thesaurus)
Some examples of endpoints are survival, improvements in quality of life, relief of symptoms, and disappearance of the tumor.
(End Point, NCI Dictionary)
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