| / English Dictionary |
EPINEPHRINE
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
A catecholamine secreted by the adrenal medulla in response to stress (trade name Adrenalin); stimulates autonomic nerve action
Synonyms:
Adrenalin; adrenaline; epinephrin; epinephrine
Classified under:
Hypernyms ("epinephrine" is a kind of...):
pressor; vasoconstrictive; vasoconstrictor (any agent that causes a narrowing of an opening of a blood vessel: cold or stress or nicotine or epinephrine or norepinephrine or angiotensin or vasopressin or certain drugs; maintains or increases blood pressure)
endocrine; hormone; internal secretion (the secretion of an endocrine gland that is transmitted by the blood to the tissue on which it has a specific effect)
neurotransmitter (a neurochemical that transmits nerve impulses across a synapse)
catecholamine (any of a group of chemicals including epinephrine and norepinephrine that are produced in the medulla of the adrenal gland)
Context examples:
It has no secretory innervation but is sensitive to epinephrine in the bloodstream.
(Apocrine Sweat Gland, NCI Thesaurus)
Nadolol competitively blocks beta-1 adrenergic receptors located in the heart and vascular smooth muscle, inhibiting the activities of the catecholamines epinephrine and norepinephrine and producing negative inotropic and chronotropic effects.
(Nadolol, NCI Thesaurus)
While such a strategy would likely not replace life-saving, emergency epinephrine when anaphylaxis occurs, therapies targeting Tfh13 cells might prevent the onset of anaphylaxis when an allergic person is exposed to an allergen.
(Scientists discover immune cell subtype in mice that drives allergic reactions, National Institutes of Health)
It is a second messenger and a key intracellular regulator, functioning as a mediator of activity for a number of hormones, including epinephrine, glucagon, and ACTH.
(Adenosine Cyclic 3',5'-Phosphate, NLM, Medical Subject Headings)
Phentermine also causes the release of epinephrine or adrenaline outside of the brain, resulting in breakdown of stored fat.
(Phentermine, NCI Thesaurus)
Agonists such as ADP, thrombin, epinephrine and collagen activate the release of APP and plasminogen activator inhibitor I (an important regulator of coagulation) from platelet storage granules.
(Platelet Amyloid Precursor Protein Pathway, NCI Thesaurus/BIOCARTA)
Dopamine is involved in movement and mood and is derived from tyrosine through newition of a hydroxyl group and decarboxylation. newitional reactions create norepinephrine and epinephrine from dopamine.
(Neurotransmitter Biosynthesis Pathway, NCI Thesaurus/BIOCARTA)
Dopamine is a naturally occurring catecholamine formed by decarboxylation of dehydroxyphenylalanine and a precursor of norepinephrine and epinephrine.
(Dopamine, NCI Thesaurus)
The bitartrate salt form of epinephrine, a direct-acting sympathomimetic amine with bronchodilator and vasoconstricting activity.
(Epinephrine Bitartrate, NCI Thesaurus)
This allele, which encodes beta-1 adrenergic receptor protein, is involved in the mediation of hormonal physiological effects from epinephrine and norepinephrine.
(ADRB1 wt Allele, NCI Thesaurus)
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