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EXON

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 I. (noun) 

Sense 1

Meaning:

Sequence of a gene's DNA that transcribes into protein structuresplay

Example:

exons are interspersed with introns

Synonyms:

coding DNA; exon

Classified under:

Nouns denoting substances

Hypernyms ("exon" is a kind of...):

deoxyribonucleic acid; desoxyribonucleic acid; DNA ((biochemistry) a long linear polymer found in the nucleus of a cell and formed from nucleotides and shaped like a double helix; associated with the transmission of genetic information)

Antonym:

intron (sequence of a eukaryotic gene's DNA that is not translated into a protein)

Credits

 Context examples: 

A fusion gene that results from a rearrangement of the q arm of chromosome 11 which fuses the exon 6 of the MLL gene to exon 8 of the CBL gene.

(MLL/CBL Fusion Gene, NCI Thesaurus)

A fusion gene that results from a chromosomal translocation t(11;19)(q23;p13.1) which fuses the first 7 exons of the MLL gene to most of the coding sequence of the ELL gene.

(MLL/ELL Fusion Gene, NCI Thesaurus)

A fusion gene that results from a chromosomal translocation t(9;11)(q34;q23) which fuses exon 7 of the MLL gene to most of the FNBP1 gene.

(MLL/FNBP1 Fusion Gene, NCI Thesaurus)

A fusion gene that results from a chromosomal translocation t(11;19)(q23;p13) which fuses the exon 6 of the MLL gene to most of the SH3GL1 gene.

(MLL/SH3GL1 Fusion Gene, NCI Thesaurus)

A fusion gene that results from a chromosomal translocation t(7;12)(q36;p13) which fuses the first exon of the MNX1 gene with exon 3 of the ETV6 gene.

(MNX1/ETV6 Fusion Gene, NCI Thesaurus)

A fusion gene that results from a chromosomal translocation t(11;12)(p15;p13) which fuses the first 13 exons of the NUP98 gene with exons 28-31 of the KDM5A gene.

(NUP98/KDM5A Fusion Gene, NCI Thesaurus)

A fusion gene (~1.9 kb) that results from a chromosomal translocation t(2;11)(q31;p15) which fuses the first twelve exons of the NUP98 gene with exon 2 of the HOXD13 gene.

(NUP98/HOXD13 Fusion Gene, NCI Thesaurus)

A fusion gene (~2.4 kb) that results from a chromosomal translocation t(11;17)(p15;p13) which fuses exon 13 of the NUP98 gene with exon 4 of the PHF23 gene.

(NUP98/PHF23 Fusion Gene, NCI Thesaurus)

A fusion gene that results from a chromosomal translocation t(11;18)(p15;q12) which fuses exon 12 of the NUP98 gene with exon 5 of the SETBP1 gene.

(NUP98/SETBP1 Fusion Gene, NCI Thesaurus)

A fusion gene that results from a chromosomal translocation t(11;20)(p15;q11) which fuses the first half of the NUP98 gene with exon 7 of the TOP1 gene.

(NUP98/TOP1 Fusion Gene, NCI Thesaurus)




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