FEEDBACK

Pronunciation (US): (GB):

I. (noun)

Sense 1

Meaning:

Response to an inquiry or experiment

Classified under:

Nouns denoting communicative processes and contents

Hypernyms ("feedback" is a kind of...):

answer; reply; response (a statement (either spoken or written) that is made to reply to a question or request or criticism or accusation)

Derivation:

feed back (respond to a query or outcome)

Sense 2

Meaning:

The process in which part of the output of a system is returned to its input in order to regulate its further output

Classified under:

Nouns denoting natural processes

Hypernyms ("feedback" is a kind of...):

action; activity; natural action; natural process (a process existing in or produced by nature (rather than by the intent of human beings))

Hyponyms (each of the following is a kind of "feedback"):

negative feedback (feedback in opposite phase with (decreasing) the input)

positive feedback; regeneration (feedback in phase with (augmenting) the input)

Derivation:

feed back (submit (information) again to a program or automatic system)

Credits

Context examples:

By inhibiting mTOR to a lesser extent than PI3K, PQR309 does not interfere with the mTOR-mediated negative feedback loop on PI3K signaling.

(pan-PI3K/mTOR Inhibitor PQR309, NCI Thesaurus)

This pathway illustrates two of the cofactor regulatory factors, MEF2 and PPARa, and an example orphan receptor feedback inhibition loop.

(PGC1a Regulation Pathway, NCI Thesaurus/BIOCARTA)

Formin-dependent activation of BMP-antagonist Gremlin induces FGF4 and the SHH/FGF4 feedback loop.

(Oncogene HST, NCI Thesaurus)

As part of a feedback loop, PKA can inhibit the activation of particulate guanylyl cyclase.

(Olfactory Transduction Pathway, NCI Thesaurus/KEGG)

Together, these lead to decreased IGF-I receptor activation and a decreased feedback to the hypothalamus and pituitary.

(Food Intake and Energy Homeostasis Pathway, NCI Thesaurus/BIOCARTA)

Mimicking the negative feedback mechanism of testosterone, nandrolone decanoate also suppresses the secretion of luteinizing hormone (LH).

(Nandrolone Decanoate, NCI Thesaurus)

BCR ligation stimulates a transient induction of MYC that leads to high level CTCF expression and feedback suppression of MYC transcription.

(CTCF Pathway, NCI Thesaurus/BIOCARTA)

Alteration of positive or negative feedback mechanisms can induce hormone release.

(Endocrine Secretory Process, NCI Thesaurus)

In the nucleus, Per and Cry form a feedback loop that inhibits transcriptional activation by Bmal1 and Clock, lowering their own expression in the process.

(Circadian Rhythm Pathway BioCarta, NCI Thesaurus/BIOCARTA)

This also removes the inhibition of PKA by DARPP-32, forming a positive feedback loop for further DARPP-32 inactivation by PKA.