| / English Dictionary |
FETOPROTEIN
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
Any of several antigens that occur naturally in the fetus and sometimes in adults with cancer
Synonyms:
fetoprotein; foetoprotein
Classified under:
Hypernyms ("fetoprotein" is a kind of...):
antigen (any substance (as a toxin or enzyme) that stimulates an immune response in the body (especially the production of antibodies))
Hyponyms (each of the following is a kind of "fetoprotein"):
AFP; alpha fetoprotein; alpha foetoprotein (an abnormally large amount of this fetoprotein in the fetus can signal an abnormality of the neural tube (as spina bifida or anencephaly))
Context examples:
After vaccination, expressed alpha fetoprotein may stimulate a cytotoxic T lymphocyte (CTL) response against tumor cells that express alpha fetoprotein, resulting in tumor cell lysis.
(Alpha Fetoprotein Adenoviral Vector Vaccine, NCI Thesaurus)
Upon administration, monoclonal antibody HuAFP31 (mAb HuAFP31) binds to and stimulates a cytotoxic T lymphocyte (CTL) response against tumor cells that express alpha fetoprotein.
(Monoclonal Antibody HuAFP31, NCI Thesaurus)
A cell-based cancer vaccine comprised of autologous dendritic cells pulsed with four alpha-fetoprotein (AFP) peptides, with potential immunostimulatory and antineoplastic activities.
(Alpha-fetoprotein Peptide-Pulsed Autologous Dendritic Cell Vaccine, NCI Thesaurus)
HuAFP31 binds to tumor cells that make alpha fetoprotein (AFP), and the indium In 111 may kill the tumor cells.
(Indium In 111 DOTA Monoclonal Antibody HuAFP31, NCI Dictionary)
HuAFP31 attaches to tumor cells that make alpha fetoprotein (AFP).
(HuAFP31, NCI Dictionary)
A measurement of the alpha fetoprotein in a biological specimen.
(Alpha-fetoprotein Measurement, NCI Thesaurus/CDISC)
A vaccine consisting of plasmid DNA encoding alpha fetoprotein.
(Alpha Fetoprotein Plasmid DNA Vaccine, NCI Thesaurus)
The determination of the amount of alpha fetoprotein L3 present in a sample.
(Alpha Fetoprotein L3 Measurement, NCI Thesaurus)
The determination of the amount of the alpha fetoprotein activity present in a sample.
(Alpha Fetoprotein Activity Measurement, NCI Thesaurus)
This allele, which encodes alpha-fetoprotein, plays a critical role in the fetal development.
(AFP wt Allele, NCI Thesaurus)
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