| / English Dictionary |
FIBRIN
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
A white insoluble fibrous protein formed by the action of thrombin on fibrinogen when blood clots; it forms a network that traps red cells and platelets
Classified under:
Hypernyms ("fibrin" is a kind of...):
protein (any of a large group of nitrogenous organic compounds that are essential constituents of living cells; consist of polymers of amino acids; essential in the diet of animals for growth and for repair of tissues; can be obtained from meat and eggs and milk and legumes)
Derivation:
fibrinous (characterized by the presence of fibrin)
Context examples:
Fibrin is a type of tumor marker.
(Fibrin, NCI Dictionary)
Apixaban directly inhibits factor Xa, thereby interfering with the conversion of prothrombin to thrombin and preventing formation of cross-linked fibrin clots.
(Apixaban, NCI Thesaurus)
The platelets retain the fibrin in tiny, tightly wound bundles, therefore remodeling the fibrin mesh to make it more dense and stiff.
(How And Why Blood Clots Shrink, The Titi Tudorancea Bulletin)
In turn, factor Xa/Va complex activates thrombin, which cleaves fibrinogen into fibrin, eventually resulting in blood clot formation.
(Antihemophilic Factor, Human Recombinant, NCI Thesaurus)
Any of the sequential processes by which coagulation factors interact to form a fibrin clot.
(Coagulation Process, NCI Thesaurus)
The vascular tissue is more abundant at the periphery of the tumor and contains fibrin thrombi.
(Angiolipoma, NCI Thesaurus)
Blood coagulation is another series of proenzyme-to-serine protease conversions, culminating the formation of thrombin, the enzyme responsible for the conversion of soluble fibrinogen to the insoluble fibrin clot.
(Complement and Coagulation Cascade, NCI Thesaurus/KEGG)
A fibrillar protein present in blood plasma; it converts to fibrin during the process of blood clot formation.
(Fibrinogen, NCI Thesaurus)
T-cell immune response with diffuse perivillous fibrin deposition associated with intrauterine growth restriction, pre-term birth and recurrent fetal loss.
(Diffuse Chronic Villitis, NCI Thesaurus)
Orthologous to human thrombin, batroxobin activates soluble fibrinogen into fibrin and facilitates blood coagulation, thereby can be used in substitution of thrombin in quantitative thrombin time test.
(Batroxobin, NCI Thesaurus)
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