| / English Dictionary |
FOLATE
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
A B vitamin that is essential for cell growth and reproduction
Synonyms:
folacin; folate; folic acid; pteroylglutamic acid; pteroylmonoglutamic acid; vitamin Bc; vitamin M
Classified under:
Hypernyms ("folate" is a kind of...):
B; B-complex vitamin; B complex; B vitamin; vitamin B; vitamin B complex (originally thought to be a single vitamin but now separated into several B vitamins)
Context examples:
Folate helps to make red blood cells.
(Folate, NCI Dictionary)
The dihydrochloride salt of nolatrexed, a water-soluble lipophilic quinazoline folate analog with antineoplastic activity.
(Nolatrexed Dihydrochloride, NCI Thesaurus)
Folate naturally in foods containing two or more glutamate molecules.
(Naturally Occurring Folate, NCI Thesaurus/CRCH)
A liposome-encapsulated formulation of the benzoquinazoline folate analog OSI-7904 with antineoplastic activity.
(OSI-7904L, NCI Thesaurus)
It belongs to the family of drugs called folate antagonists.
(Piritrexim, NCI Dictionary)
Piritrexim inhibits the enzyme dihydrofolate reductase enzyme, thereby disrupting folate metabolism and DNA synthesis and cell division.
(Piritrexim, NCI Thesaurus)
A peptide vaccine containing five immunogenic peptide epitopes of the human folate receptor alpha (FR alpha or FOLR1), including FR30, FR56, FR76, FR113, and FR238, with potential immunomodulating and antineoplastic activity.
(Multi-epitope Folate Receptor Alpha Peptide Vaccine, NCI Thesaurus)
This allele, which encodes monofunctional C1-tetrahydrofolate synthase, mitochondrial protein, plays a role in the modulation of mitochondrial folate metabolism.
(MTHFD1L wt Allele, NCI Thesaurus)
This protein plays a role in folate metabolism.
(Methylenetetrahydrofolate Reductase, NCI Thesaurus)
This protein is involved in the modulation of tetrahydrofolate synthesis and other folate metabolic processes.
(Monofunctional C1-Tetrahydrofolate Synthase, Mitochondrial, NCI Thesaurus)
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