| / English Dictionary |
GROWTH FACTOR
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
A protein that is involved in cell differentiation and growth
Classified under:
Hypernyms ("growth factor" is a kind of...):
protein (any of a large group of nitrogenous organic compounds that are essential constituents of living cells; consist of polymers of amino acids; essential in the diet of animals for growth and for repair of tissues; can be obtained from meat and eggs and milk and legumes)
Hyponyms (each of the following is a kind of "growth factor"):
nerve growth factor; NGF (a protein that is involved in the growth of peripheral nerve cells)
Context examples:
An inhibitor of the proto-oncogene c-Met (also known as hepatocyte growth factor receptor (HGFR)) with potential antineoplastic activity.
(MET Tyrosine Kinase Inhibitor SAR125844, NCI Thesaurus)
This gene plays a role in transcriptional regulation, muscle development and transcriptional responses to stress and growth factors.
(MEF2A Gene, NCI Thesaurus)
Acidic fibroblast growth factor intracellular binding protein (364 aa, 42 kD) is a cell communication process protein that is encoded by the human FIBP gene and has a role in signal transduction and B-cell activation.
(Acidic Fibroblast Growth Factor Intracellular Binding Protein, NCI Thesaurus)
It binds to a protein called hepatocyte growth factor (HGF), which may cause cancer cells to grow.
(AMG 102, NCI Dictionary)
ROS stimulated dentin production by activating transforming growth factor beta (TGF-β), a signaling protein that can promote dental stem cell differentiation.
(Laser Therapy Prompts Regeneration in Teeth, NIH)
The nerve growth factor also protects nerve cells from age-related shrinkage and wasting.
(Exercise May Help Seniors with Word, Memory Problems, The Titi Tudorancea Bulletin)
Some neurological disorders are associated with higher than normal brain levels of the growth factor TGF-beta, including Alzheimer's disease and brain injury.
(Scientists uncover nuclear process in the brain that may affect disease, NIH)
Newly acquired mutations were found in several cancer-associated genes: fibroblast growth factor receptor (FGFR2), PIK3CA, TP53, KRAS, and estrogen receptor (ESR1).
(Isolated cancer cells may lead to personalized treatments, NIH)
The link between diet and longevity appeared to be moderated by a pathway involving insulin-like growth factor 1 (IGF-1).
(Protein Consumption Linked to Longevity, NIH)
An inhibitor of the receptor tyrosine kinase Met (hepatocyte growth factor receptor) with potential antineoplastic activity.
(MET Tyrosine Kinase Inhibitor EMD 1204831, NCI Thesaurus)
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