| / English Dictionary |
HYDROCORTISONE
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
An adrenal-cortex hormone (trade names Hydrocortone or Cortef) that is active in carbohydrate and protein metabolism
Synonyms:
Cortef; cortisol; hydrocortisone; Hydrocortone
Classified under:
Hypernyms ("hydrocortisone" is a kind of...):
adrenal cortical steroid; corticoid; corticosteroid (a steroid hormone produced by the adrenal cortex or synthesized; administered as drugs they reduce swelling and decrease the body's immune response)
Context examples:
Additional steroids such as dexamethasone or hydrocortisone may also be included in this regimen.
(Docetaxel-Estramustine Regimen, NCI Thesaurus)
Hydrocortisone sodium succinate is chemically similar to the endogenous hormone that stimulates anti-inflammatory and immunosuppressive activities, in addition to exhibiting minor mineralocorticoid effects.
(Hydrocortisone Sodium Succinate, NCI Thesaurus)
As a glucocorticoid agonist, hydrocortisone promotes protein catabolism, gluconeogenesis, capillary wall stability, renal excretion of calcium, and suppression of immune and inflammatory responses.
(Clindamycin/Hydrocortisone Lotion, NCI Thesaurus)
A combination preparation containing the polypeptide antibiotic polymyxin b, the aminoglycoside antibiotic neomycin, the glucocorticoid hydrocortisone and, in some formulations, the antibiotic bacitracin zinc with antibacterial and anti-inflammatory activities.
(Cortisporin Formulation, NCI Thesaurus)
Hydrocortisone acetate initially binds to the cytoplasmic glucocorticoid receptor; then the receptor-ligand complex is translocated to the nucleus where it initiates the transcription of genes encoding for anti-inflammatory mediators, such as cytokines and lipocortins.
(Hydrocortisone Acetate, NCI Thesaurus)
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