| / English Dictionary |
HYDROXY
| Pronunciation (US): |  | (GB): | |
I. (adjective)
Sense 1
Meaning:
Being or containing a hydroxyl group
Classified under:
Relational adjectives (pertainyms)
Pertainym:
hydroxyl (the monovalent group -OH in such compounds as bases and some acids and alcohols)
Context examples:
In the body lovastatin is hydrolysed to its beta-hydroxy acid active form.
(Lovastatin Acid, NCI Thesaurus)
It is a sodium or calcium salt of [4-(alpha-(4-diethylaminophenyl)-5-hydroxy- 2,4-disulfophenyl-methylidene)-2,5-cyclohexadien-1-ylidene] diethylammonium hydroxide inner salt.
(Patent Blue V Dye, NCI Thesaurus)
SR-45023A binds to hydroxyapatite crystals in the bone matrix where it inhibits enzymatic activity of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase, which is required for the formation of mevalonate, the precursor of cholesterol.
(Apomine, NCI Thesaurus)
Colestolone targets sterol regulatory element binding protein (SREBP) which reduces the transcription of the 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMGCR) gene, the rate-limiting enzyme in the sterol pathway.
(Colestolone, NCI Thesaurus)
An organic salt containing a one to one ratio of methenamine, a heterocyclic organic compound, and mandelic acid, an aromatic alpha hydroxy acid, used in the treatment of urinary tract infections.
(Methenamine Mandelate, NCI Thesaurus)
A calcium-free, iron and magnesium hydroxy carbonate and inorganic phosphate binder with phosphate lowering activity.
(Fermagate, NCI Thesaurus)
In addition, this agent is capable of inhibiting rapid desensitization of the ionotropic alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA)-type glutamate receptors, thereby potentiating glutamate responses which may induce seizures activity.
(Cyclothiazide, NCI Thesaurus)
Fluvastatin competitively inhibits hepatic 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase, which catalyzes the conversion of HMG-CoA to mevalonate, a key step in cholesterol synthesis.
(Fluvastatin, NCI Thesaurus)
Cyclic esters of hydroxy carboxylic acids, containing a 1-oxacycloalkan-2-one structure, or analogues having unsaturation or heteroatoms replacing one or more carbon atoms of the ring (IUPAC).
(Lactone Compound, NCI Thesaurus)
Fluvastatin competitively inhibits hepatic 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase, the enzyme that catalyzes the conversion of HMG-CoA to mevalonate, a key step in cholesterol synthesis.
(Fluvastatin Sodium, NCI Thesaurus)
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