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INSOLUBLE

Pronunciation (US): Play  (GB): Play

 I. (adjective) 

Sense 1

Meaning:

Without hope of solutionplay

Example:

an insoluble problem

Classified under:

Adjectives

Similar:

hopeless (without hope because there seems to be no possibility of comfort or success)

Derivation:

insolubility (the property (of a problem or difficulty) that makes it impossible to solve)

Sense 2

Meaning:

(of a substance) incapable of being dissolvedplay

Synonyms:

indissoluble; insoluble

Classified under:

Adjectives

Similar:

non-water-soluble; water-insoluble (not soluble in water)

Antonym:

soluble ((of a substance) capable of being dissolved in some solvent (usually water))

Derivation:

insolubility (the quality of being insoluble and difficult to dissolve in liquid)

Sense 3

Meaning:

Admitting of no solution or explanationplay

Example:

an insoluble doubt

Classified under:

Adjectives

Similar:

insolvable; unresolvable; unsoluble; unsolvable (not easily solved)

Also:

incomprehensible; inexplicable (incapable of being explained or accounted for)

Antonym:

soluble (susceptible of solution or of being solved or explained)

Derivation:

insolubility (the property (of a problem or difficulty) that makes it impossible to solve)

Credits

 Context examples: 

ELPs are useful biomaterials because they can undergo phase changes—go from a soluble to an insoluble state, or vice-versa—in response to changes in temperature.

(Biomaterial Artificial Protein Helps Heal Tissue, The Titi Tudorancea Bulletin)

A sweetened and flavored insoluble plastic material of various shapes which when chewed, releases a drug substance into the oral cavity.

(Chewing Gum Dosage Form, NCI Thesaurus/CDISC)

Amyloid-beta does attach itself to lipid molecules, however, which are sticky and insoluble.

(Brain cholesterol associated with increased risk of Alzheimer’s disease, University of Cambridge)

An insoluble fraction isolated from the bacterium Corynebacterium granulosum with potential cancer immunotherapeutic activity.

(Corynebacterium Granulosum P40, NCI Thesaurus)

A water-insoluble heterocyclic amide with potential antineoplastic activity.

(Daniquidone, NCI Thesaurus)

It is insoluble in water, but soluble in ether, benzene, and certain esters.

(Paraffin, NCI Thesaurus)

Capecitabine rapidly disintegrating tablet (RDT) contains the water insoluble, disintegrating agent crospovidone which very rapidly disperses and swells in water making this RDT easier to swallow than the traditional capecitabine tablet.

(Capecitabine Rapidly Disintegrating Tablet, NCI Thesaurus)

A nanoparticle-based injectable concentrate containing the water-insoluble taxane paclitaxel, with potential antineoplastic activity.

(Paclitaxel Injection Concentrate for Nanodispersion, NCI Thesaurus)

The binding of water-insoluble rapamycin to nanoparticle albumin permits the albumin-mediated endocytosis of rapamycin by tumor cells and endothelial cells.

(Nanoparticle Albumin-Bound Rapamycin, NCI Thesaurus)

A colloidal dispersion formulation of 9-Aminocamptothecin, a water-insoluble camptothecin derivative.

(Aminocamptothecin Colloidal Dispersion, NCI Thesaurus)




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