| / English Dictionary |
KAPPA
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
The 10th letter of the Greek alphabet
Classified under:
Nouns denoting communicative processes and contents
Hypernyms ("kappa" is a kind of...):
alphabetic character; letter; letter of the alphabet (the conventional characters of the alphabet used to represent speech)
Holonyms ("kappa" is a member of...):
Greek alphabet (the alphabet used by ancient Greeks)
Context examples:
Morphine binds to and activates specific opiate receptors (delta, mu and kappa), each of which are involved in controlling different brain functions.
(Morphine, NCI Thesaurus)
Naloxone binds to mu-opioid receptors with a high affinity, and a lesser degree to kappa- and gamma-opioid receptors in the CNS.
(Naloxone, NCI Thesaurus)
A fully human monoclonal antibody directed against the receptor activator of nuclear factor kappa beta ligand (RANKL) with antiosteoclast activity.
(Denosumab, NCI Thesaurus)
DAI is the first identified sensor of cytosolic DNA which activates the IRF and NF-kappa B transcription factors, leading to production of type I interferon and other cytokines.
(Cytosolic DNA-Sensing Pathway, NCI Thesaurus/KEGG)
A humanized immunoglobulin IgG1 kappa monoclonal antibody directed against the B-cell-specific membrane protein CD-19 with potential immunostimulating and antineoplastic activities.
(Anti-CD19 Monoclonal Antibody MEDI-551, NCI Thesaurus)
Alemtuzumab is an IgG1 kappa with human variable framework and constant regions, and complementarity-determining regions derived from a rat monoclonal antibody.
(Alemtuzumab, NCI Thesaurus)
Capromab, an IgG1 kappa immunoglobulin, binds specifically to a cytoplasmic epitope of prostate-specific membrane glycoprotein (PSMA) that is only expressed by prostatic epithelial cells (benign and malignant).
(Capromab pendetide, NCI Thesaurus)
Upon administration, caffeic acid phenethyl ester (CAPE) inhibits the activation of nuclear transcription factor NF-kappa B and may suppress p70S6K and Akt-driven signaling pathways.
(Caffeic Acid Phenethyl Ester, NCI Thesaurus)
A human IgG1 kappa monoclonal antibody directed against human CC chemokine ligand 2 (CCL2) with potential antineoplastic activity.
(Carlumab, NCI Thesaurus)
The pathway downstream of TRAFs activates the transcription factor NF-kappaB through a kinase pathway involving map kinases, NIK (NF-kappaB inducing kinase) and I-kappa B kinases.
(CD40L Signaling Pathway, NCI Thesaurus/BIOCARTA)
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